Peri-ictal electrocardiographic alterations in paediatric epilepsy patients. A prospective studyAlteraciones electrocardiográficas periictales en pacientes pediátricos con epilepsia. Un estudio prospectivo

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dc.article.number102546
dc.article.number102546
dc.contributor.authorRamírez K.
dc.contributor.authorMesa T.
dc.contributor.authorAcevedo K.
dc.contributor.authorFrangini P.
dc.contributor.authorMolina V.
dc.date.accessioned2025-05-01T10:32:06Z
dc.date.available2025-05-01T10:32:06Z
dc.date.issued2021
dc.description.abstract© 2021 Revista de Neurologia. All rights reserved.Introduction. Epileptic seizures can be associated with peri-ictal heart rhythm disorders and even sudden death (SUDEP). Few paediatric studies have been conducted on the subject. Aim. To determine heart rhythm disorders in paediatric patients with epilepsy who were studied with videoelectroencephalogram (video-EEG). Methods. Prospective, observational study in patients under 18 years of age admitted for video-EEG at the Hospital Clínico Red de Salud UC-Christus, Santiago, Chile. A neurological and cardiological evaluation and electrocardiogram (ECG) were performed, in addition to a Holter ECG simultaneously with the video-EEG. Results. Twenty-five patients were studied, 12 with refractory epilepsies, 23/25 focal and 20 on polytherapy. Altogether 768 hours of video-EEG were recorded, including 281 seizures in 15 patients: 157 clinical and 103 generalised. There were no serious arrhythmias, only non-specific or probably benign disorders, mainly incomplete right bundle branch block in 11 patients, which were more frequent in refractory epilepsies (p<0.036). Heart rate variation occurred mainly in seizures >30 seconds. No patient presented SUDEP. Conclusions. This is the first prospective study, with a new technique, using video-EEG and Holter ECG simultaneously in paediatrics. Despite the high number of seizures and refractory patients, we found no serious heart rhythm disorders, consistent with the clinical evaluation. Right bundle branch block is considered a non-pathological cardiological finding, but was highly prevalent in our sample compared to the normal population, especially in refractory epilepsy. Given that this is a serious event in epilepsy, it is important to further investigate such studies to assess preventive measures.
dc.description.funderFONDECYT
dc.description.funderMarine Energy Research & Innovation Center
dc.format.extent15 páginas
dc.fuente.origenScopus
dc.identifier.doi10.33588/RN.7204.2020368
dc.identifier.eisbn978-84-9880-797-4
dc.identifier.eissn18667929
dc.identifier.isbn978-0-12-817240-7
dc.identifier.issn02100010
dc.identifier.pubmedid33570157
dc.identifier.scieloidS0718-69242020000300109
dc.identifier.scopusidSCOPUS_ID:85101454122
dc.identifier.urihttps://doi.org/10.33588/RN.7204.2020368
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/103822
dc.identifier.wosidWOS:000624959300001
dc.information.autorucEscuela de Medicina; Acevedo Gallinato Keryma Alejandra; S/I; 86517
dc.information.autorucEscuela de Medicina; Frangini Sanhueza Patricia Andrea; S/I; 1617
dc.information.autorucEscuela de Medicina; Mesa Latorre Manuel Tomas; S/I; 99641
dc.issue.numero3515
dc.language.isoes
dc.nota.accesoSin adjunto
dc.pagina.final111
dc.pagina.inicio105
dc.publisherAcademic Press
dc.relation.ispartof7th Workshop On Educational Innovation In Architecture (JIDA), NOV 14-15, 2019, Madrid, SPAIN
dc.revistaRevista de Neurologia
dc.rightsAcceso cerrado
dc.subjectArrhythmia
dc.subjectAsystole
dc.subjectElectrocardiogram
dc.subjectEpilepsy
dc.subjectHolter
dc.subjectQT
dc.subjectRefractory epilepsy
dc.subjectSudden death
dc.subjectSUDEP
dc.subjectVideo-EEG
dc.subject.ddc510
dc.subject.deweyMatemática física y químicaes_ES
dc.subject.ods02 Zero hunger
dc.subject.odspa02 Hambre cero
dc.titlePeri-ictal electrocardiographic alterations in paediatric epilepsy patients. A prospective studyAlteraciones electrocardiográficas periictales en pacientes pediátricos con epilepsia. Un estudio prospectivo
dc.typeartículo
dc.volumen72
sipa.codpersvinculados86517
sipa.codpersvinculados1617
sipa.codpersvinculados99641
sipa.indexScopus
sipa.indexPubmed
sipa.trazabilidadCarga WOS-SCOPUS;01-05-2025
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