Randomized study comparing duty-cycled bipolar and unipolar radiofrequency with point-by-point ablation in pulmonary vein isolation

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dc.contributor.authorBittner, Alex
dc.contributor.authorMoennig, Gerold
dc.contributor.authorZellerhoff, Stephan
dc.contributor.authorPott, Christian
dc.contributor.authorKoebe, Julia
dc.contributor.authorDechering, Dirk
dc.contributor.authorMilberg, Peter
dc.contributor.authorWasmer, Kristina
dc.contributor.authorEckardt, Lars
dc.date.accessioned2024-01-10T13:17:00Z
dc.date.available2024-01-10T13:17:00Z
dc.date.issued2011
dc.description.abstractBACKGROUND Pulmonary vein (PV) electrical isolation is a therapeutic option in atrial fibrillation (AF). New technologies may reduce the complexity of the procedure.
dc.description.abstractOBJECTIVE The aim of the present study was to compare immediate results and short-term efficacy of a new circular ablation catheter (PVAC) with a conventional point-by-point ablation.
dc.description.abstractMETHODS The prospective study enrolled 80 consecutive patients with paroxysmal AF or persistent AF, refractory to antiarrhythmic drugs, who were randomized to radiofrequency ablation using duty-cycled bipolar and unipolar radiofrequency by a decapolar circular catheter (PVAC group) or to point-by-point ablation supported by a 3-dimensional mapping system (3D group).
dc.description.abstractRESULTS Forty patients per group were included. Mean age was 58 +/- 10 years, 64% were male; 55% had paroxysmal AF, 45% had persistent AF. There were no significant differences between groups. Complete electrical isolation was reached in all but 1 PV, which was not isolated in the PVAC group because of phrenic nerve capture. Procedure and fluoroscopy times were lower in the PVAC group: 171 +/- 40 minutes vs. 224 +/- 27 minutes, P < .001; 26 +/- 8 minutes vs. 35 +/- 9 minutes, P < .001; respectively. There were no major complications. During a mean follow-up of 254 +/- 99 days, 72% in the PVAC group and 68% in the 3D group were free of AF recurrences irrespective of the initial AF type (P = NS).
dc.description.abstractCONCLUSION PVAC represents a safe alternative for PV isolation. It reduces both procedure and fluoroscopy time. The short- and middle-term efficacy is comparable to a conventional point-by point antral ablation technique.
dc.description.funderAstra/Zeneca
dc.description.funderBiosense Webster
dc.description.funderBiotronik
dc.description.funderBoehringer Ingelheim
dc.description.funderGuidant
dc.description.funderMedtronic
dc.description.funderSanofi Aventis
dc.description.funderSt. Jude Medical
dc.description.funderSanofi
dc.description.funderOsypka
dc.description.funderUniversity of Muenster, Germany
dc.fechaingreso.objetodigital25-03-2024
dc.format.extent8 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.hrthm.2011.03.051
dc.identifier.eissn1556-3871
dc.identifier.issn1547-5271
dc.identifier.pubmedidMEDLINE:21457793
dc.identifier.urihttps://doi.org/10.1016/j.hrthm.2011.03.051
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/78629
dc.identifier.wosidWOS:000294249200005
dc.information.autorucMedicina;Bittner A ;S/I;1000416
dc.issue.numero9
dc.language.isoen
dc.nota.accesocontenido parcial
dc.pagina.final1390
dc.pagina.inicio1383
dc.publisherELSEVIER SCIENCE INC
dc.revistaHEART RHYTHM
dc.rightsacceso restringido
dc.subjectAtrial fibrillation ablation
dc.subjectpulmonary vein isolation
dc.subjectduty-cycled bipolar and unipolar radiofrequency
dc.subjectPAROXYSMAL ATRIAL-FIBRILLATION
dc.subjectCATHETER ABLATION
dc.subjectMANAGEMENT
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleRandomized study comparing duty-cycled bipolar and unipolar radiofrequency with point-by-point ablation in pulmonary vein isolation
dc.typeartículo
dc.volumen8
sipa.codpersvinculados1000416
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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