Distribution, frequency and clinical presentation of leptospirosis and coinfections: a systematic review protocol

dc.catalogadorgrr
dc.contributor.authorParra Barrera, Eliana L.
dc.contributor.authorBello, Solmara
dc.contributor.authorGallego-Lopez, Gina M.
dc.contributor.authorAtero Fredericksen, Nicolhole Alejandra
dc.contributor.authorReyes Santamaria, Elízabeth
dc.contributor.authorBautista, Adriana
dc.date.accessioned2024-11-25T14:28:34Z
dc.date.available2024-11-25T14:28:34Z
dc.date.issued2022
dc.description.abstractIntroduction: Leptospirosis is a zoonotic disease with high prevalence in low- income and middle- income countries and tropical and subtropical regions. The clinical symptoms of the disease are similar to symptoms presented by other endemic infectious diseases that could be present simultaneously. Thus, leptospirosis could be masked by similar infections like dengue, malaria, hantavirus, melioidosis and borreliosis, among others. Therefore, leptospirosis could present itself as an under- reported infection or as a coinfection with another pathogen, as has been reported in the literature. However, there is a lack of documented evidence about the specific risk factors of leptospirosis infection, the symptoms, the coinfection’s mortality and the frequency of coinfection. Additionally, leptospirosis coinfections have not been considered a neglected public health concern. Therefore, this systematic review aims to evaluate published articles that show the risk factors associated with leptospirosis infection and coinfection with other pathogens. Methods and analysis The search process to identify eligible studies will be conducted including the LILACS, ProQuest, PubMed and Scopus databases with no restriction in terms of publication date. Also, grey literature will be included in the research. Authors will independently screen the title and abstracts of the articles identified from the search using Rayyan free software. Eligibility criteria include peer- reviewed research articles written in English or Spanish, including observational studies, cohorts, casecontrol, cross- sectional, ecological studies and report cases. The systematic review will include studies that report descriptions of leptospirosis cases with coinfection or co- occurrence. The search will be accomplished by articles from 1950 to May 2022. The data will be extracted in a standard extraction form using an Excel format. Ethics and dissemination Results will be published in a peer- reviewed journal. Also, findings will be disseminated through scientific meetings. Ethical approval will not be required as this is a systematic review and primary data will be not collected or included. PROSPERO registration number CRD42021234754.
dc.fechaingreso.objetodigital2024-11-25
dc.identifier.doi10.1136/bmjopen-2021-055187
dc.identifier.eissn20446055
dc.identifier.issn20446055
dc.identifier.pubmedid36526310
dc.identifier.scopusidSCOPUS_ID:85144590134
dc.identifier.urihttps://doi.org/10.1136/bmjopen-2021-055187
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/88664
dc.identifier.wosidWOS:000920894900005
dc.information.autorucEscuela de Medicina; Atero Fredericksen, Nicolhole Alejandra; 0000-0002-4312-1609; 1124121
dc.issue.numero12
dc.language.isoen
dc.nota.accesocontenido completo
dc.pagina.inicioe055187
dc.revistaBMJ open
dc.rightsacceso abierto
dc.rights.licenseCC BY-NC 4.0 Attribution-NonCommercial 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/deed.en
dc.subjectDiagnostic microbiology
dc.subjectEpidemiology
dc.subjectInfection control
dc.subjectInfectious diseases
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good health and well-being
dc.subject.odspa03 Salud y bienestar
dc.titleDistribution, frequency and clinical presentation of leptospirosis and coinfections: a systematic review protocol
dc.typeartículo
dc.volumen12
sipa.codpersvinculados1124121
sipa.trazabilidadSCOPUS;02-03-2023
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