First Case report of Lawsonella clevelandensis Infection in Latin America and literature reviewReporte del primer caso de infección por Lawsonella clevelandensis en Latinoamérica y revisión de literatura

Simple item page
dc.catalogadorjwg
dc.contributor.authorZavadzki, Giovanna
dc.contributor.authorReyes Barros, Tomas Alejandro
dc.contributor.authorSarfatis Feig, Alberto
dc.contributor.authorGranada Castaño, Jaime
dc.contributor.authorKobus Garin, Valentina
dc.contributor.authorRamos-Rojas, Jaime
dc.contributor.authorBigossi Aguiar, Natalia
dc.contributor.authorInzunza Robles, José Francisco
dc.date.accessioned2025-03-18T15:51:12Z
dc.date.available2025-03-18T15:51:12Z
dc.date.issued2023
dc.description.abstractAll rights reserved.Lawsonella clevelandensis is a gram-positive anaerobic bacillus, partially acid-fast, belonging to the order Corynebacteriales and is considered commensal of the skin and oral cavity. In recent years, few cases of infection by this microorganism have been reported, generally in immunosuppressed patients, with the most reported clinical presentation being the generation of abscesses. The isolation of this bacterium is difficult since it does not grow in traditional cultures, so its identification usually requires the use of molecular biology. We present the case of a 29-year-old patient with a kidney transplant and progressive worsening of kidney function in the context of a pauci-immune vasculitis which required greater immunosuppression. During the investigation, it was identified an asymptomatic leukocyturia, with a negative urine culture, for which six urine smear microscopy tests were performed of which 3 were positive, but with a negative Koch culture. Sequencing of the gene that codes for the 16s RNA of the bacterial ribosome was performed from a urine sample, obtaining a sequence compatible with Lawsonella clevelandensis. After the result, therapy with amoxicillin-clavulanic acid was indicated with resolution of the leukocyturia and negative smear microscopy, and immunosuppression could be indicated without inconvenience. To the authors' knowledge, this is the twelfth case of Lawsonella clevelandensis infection described in the medical literature in the world and the first to report the isolation of the pathogen in urine.
dc.fuente.origenORCID
dc.identifier.doi10.4067/s0034-98872023000700941
dc.identifier.issn07176163 00349887
dc.identifier.scopusidSCOPUS_ID:85198973547
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/102739
dc.information.autorucActividades Universitarias-Dri; Zavadzki Giovanna; S/I; 1181693
dc.information.autorucEscuela de Medicina; Reyes Barros Tomas Alejandro; 0000-0003-0612-0006; 187158
dc.information.autorucEscuela de Medicina; Inzunza Robles Jose Francisco; S/I; 1076992
dc.language.isoen
dc.nota.accesocontenido parcial
dc.pagina.final946
dc.pagina.inicio941
dc.publisherSociedad Medica de Santiago
dc.revistaRevista Medica de Chile
dc.rightsacceso restringido
dc.subjectBacteria Renal Insufficiency, Chronic
dc.subjectBacterial Infections
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good health and well-being
dc.subject.odspa03 Salud y bienestar
dc.titleFirst Case report of Lawsonella clevelandensis Infection in Latin America and literature reviewReporte del primer caso de infección por Lawsonella clevelandensis en Latinoamérica y revisión de literatura
dc.typeartículo
dc.volumen151
sipa.codpersvinculados1181693
sipa.codpersvinculados187158
sipa.codpersvinculados1076992
sipa.trazabilidadORCID;2025-03-03
Files
Collections
Artículos de revistas