The role of respiratory syncytial virus‐ and rhinovirus‐induced bronchiolitis in recurrent wheeze and asthma—A systematic review and meta‐analysis

Simple item page
dc.contributor.authorMakrinioti, Heidi
dc.contributor.authorHasegawa, Kohei
dc.contributor.authorLakoumentas, John
dc.contributor.authorXepapadaki, Paraskevi
dc.contributor.authorTsolia, Maria
dc.contributor.authorCastro‐Rodriguez, Jose A.
dc.contributor.authorFeleszko, Wojciech
dc.contributor.authorJartti, Tuomas
dc.contributor.authorJohnston, Sebastian L.
dc.contributor.authorBush, Andrew
dc.contributor.authorPapaevangelou, Vasiliki
dc.contributor.authorCamargo, Jr., Carlos A.
dc.contributor.authorPapadopoulos, Nikolaos G.
dc.date.accessioned2023-05-19T20:25:21Z
dc.date.available2023-05-19T20:25:21Z
dc.date.issued2022
dc.description.abstractIntroduction Respiratory syncytial virus (RSV) is the most common cause of bronchiolitis. RSV-induced bronchiolitis has been associated with preschool wheeze and asthma in cohort studies where the comparison groups consist of healthy infants. However, recent studies identify rhinovirus (RV)-induced bronchiolitis as a potentially stronger risk factor for recurrent wheeze and asthma. Aim This systematic review and meta-analysis aimed to compare the associations of RSV- and RV-induced bronchiolitis with the development of preschool wheeze and childhood asthma. Methods We performed a systematic search of the published literature in five databases by using a MeSH term-based algorithm. Cohort studies that enrolled infants with bronchiolitis were included. The primary outcomes were recurrent wheeze and asthma diagnosis. Wald risk ratios and odds ratios (ORs) were estimated, along with their 95% confidence intervals (CIs). Individual and summary ORs were visualized with forest plots. Results There were 38 studies included in the meta-analysis. Meta-analysis of eight studies that had data on the association between infant bronchiolitis and recurrent wheeze showed that the RV-bronchiolitis group were more likely to develop recurrent wheeze than the RSV-bronchiolitis group (OR 4.11; 95% CI 2.24-7.56). Similarly, meta-analysis of the nine studies that had data on asthma development showed that the RV-bronchiolitis group were more likely to develop asthma (OR 2.72; 95% CI 1.48-4.99). Conclusion This is the first meta-analysis that directly compares between-virus differences in the magnitude of virus-recurrent wheeze and virus-childhood asthma outcomes. RV-induced bronchiolitis was more strongly associated with the risk of developing wheeze and childhood asthma.
dc.fechaingreso.objetodigital2024-11-26
dc.fuente.origenORCID-mayo23
dc.identifier.doi10.1111/pai.13741
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/67371
dc.identifier.wosidWOS:000773304100006
dc.issue.numeroNo. 3
dc.language.isoen
dc.nota.accesocontenido parcial
dc.revistaPediatric Allergy and Immunology
dc.rightsacceso restringido
dc.subject.ods03 Good health and well-being
dc.subject.odspa03 Salud y bienestar
dc.titleThe role of respiratory syncytial virus‐ and rhinovirus‐induced bronchiolitis in recurrent wheeze and asthma—A systematic review and meta‐analysises_ES
dc.typeartículo
dc.volumenVol. 33
sipa.indexWOS
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
The role of respiratory syncytial virus and rhinovirus induced bronchiolitis in recurrent wheeze and asthma A systematic review and meta analysis.pdf
Size:
115.01 KB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Artículos de revistas