Validation of the CALL score as a mortality prediction tool in a cohort of hospitalized COVID-19 patients in Chile

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dc.contributor.authorSanhueza, Matias
dc.contributor.authorBarrera, Manuel
dc.contributor.authorPedemonte, Juan C.
dc.contributor.authorRojas, Luis
dc.date.accessioned2025-01-20T17:35:25Z
dc.date.available2025-01-20T17:35:25Z
dc.date.issued2023
dc.description.abstractIntroduction: The CALL score is a predictive tool for respiratory failure progression inCOVID-19. Whether theCALL score is useful to predict short- andmedium-term mortality in an unvaccinated population is unknown.
dc.description.abstractMaterials and methods: This is a prospective cohort study in unvaccinated inpatients with a COVID-19 pneumonia diagnosis upon hospital admission. Patients were followed up for mortality at 28 days, 3, 6, and 12 months. Associations between CALL score and mortality were analyzed using logistic regression. The prediction performance was evaluated using the area under a receiver operating characteristic curve (AUROC).
dc.description.abstractResults: A total of 592 patients were included. On average, the CALL score was 9.25 (+/- 2). Higher CALL scores were associated with increased mortality at 28 days [univariate: odds ratio (OR) 1.58 (95% CI, 1.34-1.88), p < 0.001; multivariate: OR 1.54 (95% CI, 1.26-1.87), p < 0.001] and 12 months [univariate OR 1.63 (95% CI, 1.38-1.93), p < 0.001; multivariate OR 1.63 (95% CI, 1.35-1.97), p < 0.001]. The prediction performance was good for both univariate [AUROC 0.739 (0.687-0.791) at 28 days and 0.869 (0.828-0.91) at 12 months] and multivariate models [AUROC 0.752 (0.704-0.8) at 28 days and 0.862 (0.82-0.905) at 12 months].
dc.description.abstractConclusion: The CALL score exhibits a good predictive capacity for short- and medium-term mortality in an unvaccinated population.
dc.fuente.origenWOS
dc.identifier.doi10.3389/fmed.2023.1164615
dc.identifier.eissn2296-858X
dc.identifier.urihttps://doi.org/10.3389/fmed.2023.1164615
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/91673
dc.identifier.wosidWOS:001065109200001
dc.language.isoen
dc.revistaFrontiers in medicine
dc.rightsacceso restringido
dc.subjectCALL score
dc.subjectCOVID-19
dc.subjectmortality
dc.subjectprediction
dc.subjectinpatients
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleValidation of the CALL score as a mortality prediction tool in a cohort of hospitalized COVID-19 patients in Chile
dc.typeartículo
dc.volumen10
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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