Exploring neuroinflammation: A key driver in neuropathic pain disorders

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dc.catalogadorjlo
dc.contributor.authorScheuren, Paulina S.
dc.contributor.authorCalvo Bascuñán, Margarita
dc.date.accessioned2025-07-09T14:43:48Z
dc.date.available2025-07-09T14:43:48Z
dc.date.issued2024
dc.description.abstractInflammation is a fundamental part of the body's natural defense mechanism, involving immune cells and inflammatory mediators to promote healing and protect against harm. In the event of a lesion or disease of the somatosensory nervous system, inflammation, however, triggers a cascade of changes in both the peripheral and central nervous systems, ultimately contributing to chronic neuropathic pain. Substantial evidence links neuroinflammation to various conditions associated with neuropathic pain. This chapter will explore the role of neuroinflammation in the initiation, maintenance, and resolution of peripheral and central neuropathic pain. Additionally, biomarkers of neuroinflammation in humans will be examined, emphasizing their relevance in different neuropathic pain disorders.
dc.format.extent27 páginas
dc.fuente.origenSCOPUS
dc.identifier.doi10.1016/bs.irn.2024.10.009
dc.identifier.issn0074-7742
dc.identifier.scopusidSCOPUS_ID:85208478475
dc.identifier.urihttps://doi.org/10.1016/bs.irn.2024.10.009
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/104884
dc.information.autorucEscuela de Medicina; Calvo Bascuñán, Margarita; 0000-0003-3349-9189; 3457
dc.language.isoen
dc.nota.accesocontenido parcial
dc.pagina.final338
dc.pagina.inicio311
dc.revistaInternational Review of Neurobiology
dc.rightsacceso restringido
dc.subjectBiomarkers of inflammation
dc.subjectCentral sensitization
dc.subjectImmune cells
dc.subjectImmune system
dc.subjectInflammatory mediators
dc.subjectNeuroinflammation
dc.subjectPeripheral sensitization
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.titleExploring neuroinflammation: A key driver in neuropathic pain disorders
dc.typeartículo
dc.volumen179
sipa.codpersvinculados3457
sipa.trazabilidadSCOPUS;2024-11-17
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