Short communication: Effect of vitamins E and C on cortisol production by bovine adrenocortical cells in vitro

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dc.contributor.authorMontalvo, C. P.
dc.contributor.authorDiaz, N. H.
dc.contributor.authorGaidames, L. A.
dc.contributor.authorAndres, M. E.
dc.contributor.authorLarrain, R. E.
dc.date.accessioned2025-01-21T00:01:39Z
dc.date.available2025-01-21T00:01:39Z
dc.date.issued2011
dc.description.abstractThe aim was to determine if vitamins E and C inhibit the release of cortisol from bovine adrenocortical cells when stimulated with ACTH in vitro. A factorial arrangement of treatments was used to culture bovine adrenocortical cells with different concentrations of vitamins E and C [(+)-alpha-tocopherol at 0, 2.3, and 16 mu M and L-ascorbic acid at 0; 15, and 50 mu M]. After 3 and 7 d of vitamin treatments; cell cultures were stimulated with ACTH (1 nM) for 24 h and the culture medium extracted to measure cortisol released by the cells using HPLC with UV detection. Vitamin E, vitamin C, or their combination did not affect the amount of cortisol released by the adrenal cultures to the media. Cortisol released by the adrenal cultures ranged from 33.6 +/- 6.85 to 49.7 +/- 8.01 nmol per 10(7) cells. The modulation effect of vitamins E and C on the stress response does not take place at the cortex of the adrenal gland.
dc.fuente.origenWOS
dc.identifier.doi10.3168/jds.2010-3760
dc.identifier.eissn1525-3198
dc.identifier.issn0022-0302
dc.identifier.urihttps://doi.org/10.3168/jds.2010-3760
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/95389
dc.identifier.wosidWOS:000291827600031
dc.issue.numero7
dc.language.isoen
dc.pagina.final3497
dc.pagina.inicio3495
dc.revistaJournal of dairy science
dc.rightsacceso restringido
dc.subjectcattle
dc.subjectcortisol
dc.subjectvitamin C
dc.subjectvitamin E
dc.subject.ods13 Climate Action
dc.subject.odspa13 Acción por el clima
dc.titleShort communication: Effect of vitamins E and C on cortisol production by bovine adrenocortical cells in vitro
dc.typeartículo
dc.volumen94
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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