CORELEASE OF NEUROPEPTIDE-Y (NPY) AND NORADRENALINE FROM THE SYMPATHETIC-NERVE TERMINALS SUPPLYING THE RAT VAS-DEFERENS - INFLUENCE OF CALCIUM AND THE STIMULATION INTENSITY

Simple item page
dc.contributor.authorTORRES, G
dc.contributor.authorBITRAN, M
dc.contributor.authorHUIDOBROTORO, JP
dc.date.accessioned2025-01-23T19:21:58Z
dc.date.available2025-01-23T19:21:58Z
dc.date.issued1992
dc.description.abstractEpididymal (E) and prostatic (P) segments of the rat vas deferens were incubated with tritium-labeled noradrenaline (NA); upon transmural electrical stimulation for 20 or 60 s (70 V, 1 ms, 3-35 Hz), the outflow of immunoreactive neuropeptide Y (ir-NPY) and NA was detected in the superfusion media. Ir-NPY was detected only following trains of 35 Hz for 60 s in both E and P. In contrast, tritium was released in a graded fashion following trains of 3, 15 or 35 Hz stimulation for 60 s in E, whereas in P it reached a plateau at frequencies larger than 15 Hz. The outflow of tritium, under present conditions, was dependent on the duration of the stimuli, while the release of ir-NPY was only evoked with stimuli of 60 s duration. In the absence of external Ca2+, neurotransmission was blocked and co-release of ir-NPY and NA was prevented.
dc.fuente.origenWOS
dc.identifier.issn0304-3940
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/98923
dc.identifier.wosidWOS:A1992KF56400010
dc.issue.numero1-2
dc.language.isoen
dc.pagina.final42
dc.pagina.inicio39
dc.revistaNeuroscience letters
dc.rightsacceso restringido
dc.subjectNPY
dc.subjectNPY RELEASE
dc.subjectNPY/NA CORELEASE
dc.subjectSYMPATHETIC NEUROTRANSMISSION
dc.subjectVAS DEFERENS
dc.subjectRAT
dc.subject.ods02 Zero Hunger
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa02 Hambre cero
dc.subject.odspa03 Salud y bienestar
dc.titleCORELEASE OF NEUROPEPTIDE-Y (NPY) AND NORADRENALINE FROM THE SYMPATHETIC-NERVE TERMINALS SUPPLYING THE RAT VAS-DEFERENS - INFLUENCE OF CALCIUM AND THE STIMULATION INTENSITY
dc.typeartículo
dc.volumen148
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
Files
Collections
Artículos de revistas