Synthesis of benzo[b]thiophene carboxamides connected to 4-arylpiperazines through a benzylic spacer: Potential Ligands with 5-HT1A binding affinity

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dc.contributor.authorPessoa Mahana, Hernan
dc.contributor.authorAcevedo, R.
dc.contributor.authorAraya Maturana, Ramiro
dc.contributor.authorSaitz, Claudio
dc.contributor.authorPessoa Mahana, C. David
dc.date.accessioned2024-01-10T14:21:49Z
dc.date.available2024-01-10T14:21:49Z
dc.date.issued2007
dc.description.abstractNew benzothiophene arylpiperazine derivatives 8 (a-f) were synthesized as potential serotoninergic agents with 5-HT1A receptor affinity. Preparation of the derivatives was performed by treating N-[2-(chloromethyl)phenyl]-4,7-dimethoxybenzo[b]thiophene-2-carboxamide (7) with a series of substituted 4-arylpiperazines.
dc.fechaingreso.objetodigital2024-05-06
dc.format.extent9 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1080/00397910701557499
dc.identifier.eissn1532-2432
dc.identifier.issn0039-7911
dc.identifier.urihttps://doi.org/10.1080/00397910701557499
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/79790
dc.identifier.wosidWOS:000250737500031
dc.information.autorucQuímica;Pessoa-Mahana CD;S/I;76905
dc.issue.numero19-21
dc.language.isoen
dc.nota.accesocontenido parcial
dc.pagina.final3567
dc.pagina.inicio3559
dc.publisherTAYLOR & FRANCIS INC
dc.revistaSYNTHETIC COMMUNICATIONS
dc.rightsacceso restringido
dc.subjectarylpiperazines
dc.subjectbenzothiophene
dc.subjectdepression
dc.subject5-HT1A
dc.subjectDUAL 5-HT1A
dc.subjectDERIVATIVES
dc.subjectARYLPIPERAZINES
dc.subjectANTIDEPRESSANTS
dc.subjectQUINONES
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleSynthesis of benzo[b]thiophene carboxamides connected to 4-arylpiperazines through a benzylic spacer: Potential Ligands with 5-HT1A binding affinity
dc.typeartículo
dc.volumen37
sipa.codpersvinculados76905
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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