Chronic exposure to fine particles (PM<sub>2.5</sub>) and mortality: Evidence from Chile

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dc.contributor.authorBusch, Pablo
dc.contributor.authorCifuentes, Luis Abdon
dc.contributor.authorCabrera, Camila
dc.date.accessioned2025-01-20T20:09:59Z
dc.date.available2025-01-20T20:09:59Z
dc.date.issued2023
dc.description.abstractBackground:Many Chilean cities suffer from high air pollution from industrial, mobile, and residential wood-burning sources. Several studies have linked PM2.5 air pollution exposure to higher mortality risk from cardiovascular, pulmonary, and lung cancer causes. In recent years, Chile has developed an extensive air pollution monitoring network to enforce air quality standards for PM2.5, allowing the study of the medium-term association between PM2.5 and mortality. Methods:A negative binomial regression model was used to study the association between 3-year average PM2.5 concentrations and age-adjusted mortality rates for 105 of the 345 municipalities in Chile. Models were fitted for all (ICD10 A to Q codes), cardiopulmonary (I and J), cardiovascular (I), pulmonary (J), cancer (C), and lung cancer (C33-C34) causes; controlling for meteorological, socioeconomic, and demographic characteristics. Results:A significant association of PM2.5 exposure with cardiopulmonary (relative risk for 10 mu g/m(3) PM2.5: 1.06; 95% confidence interval = 1.00, 1.13) and pulmonary (1.11; 1.02, 1.20) age-adjusted mortality rates was found. Cardiovascular (1.06; 0.99, 1.13) and all causes (1.02; 0.98, 1.07) were positive, but not significant. No significant association was found between cancer and lung cancer. The positive associations remained even when controlling for multiple confounding factors, model specifications, and when considering different methods for exposure characterization. These estimates are in line with results from cohort studies from the United States and European studies. Conclusion:Three-year average PM2.5 exposure is positively associated with the age-adjusted mortality rate for cardiopulmonary and cardiovascular causes in Chile. This provides evidence of the medium-term exposure effect of fine particles on long-term mortality rates.
dc.description.funderInter-American Development Bank
dc.fuente.origenWOS
dc.identifier.doi10.1097/EE9.0000000000000253
dc.identifier.eissn2474-7882
dc.identifier.urihttps://doi.org/10.1097/EE9.0000000000000253
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/92033
dc.identifier.wosidWOS:001010294600001
dc.issue.numero4
dc.language.isoen
dc.revistaEnvironmental epidemiology
dc.rightsacceso restringido
dc.subjectAir pollution
dc.subjectEcological study
dc.subjectMiddle-income countries
dc.subjectMortality rates
dc.subjectPM2 5
dc.subject.ods11 Sustainable Cities and Communities
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa11 Ciudades y comunidades sostenibles
dc.subject.odspa03 Salud y bienestar
dc.titleChronic exposure to fine particles (PM<sub>2.5</sub>) and mortality: Evidence from Chile
dc.typeartículo
dc.volumen7
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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