Captopril scintigraphy in the study of arterial hypertension in pediatrics

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dc.contributor.authorLagomarsino, E
dc.contributor.authorOrellana, P
dc.contributor.authorMuñoz, J
dc.contributor.authorVelásquez, C
dc.contributor.authorCavagnaro, F
dc.contributor.authorValdés, F
dc.date.accessioned2025-01-21T01:08:33Z
dc.date.available2025-01-21T01:08:33Z
dc.date.issued2004
dc.description.abstractRenovascular hypertension (RVH) is responsible for 10% of arterial hypertension in children. The early diagnosis of RVH permits specific treatment leading to the cure of hypertension and avoidance of parenchymal damage. Captopril renal scintigraphy (CRS) provides information on the renovascular cause of the arterial hypertension. To validate the usefulness of CRS in hypertensive children, clinical, scintigraphic, and radiological data from 20 patients (mean age 6.1 +/- 5.5 years) were reviewed. Two patients were newborns. All had renal ultrasound scans and 9 had aortograms. In 7 children, RVH was confirmed by angiography, and CRS was positive for RVH in 6 of these. CRS was negative for RVH in 12 of 13 children without RVH. CRS was nondiagnostic in 3 children with abnormal baseline renal scintigraphy and severely decreased relative renal function (It;35%), 1 of whom had RVH. No side effects of captopril renography were observed. Captopril renography provides a logical, non-invasive, safe, and cost-effective approach in the evaluation of children suspected of having RVH.
dc.fuente.origenWOS
dc.identifier.doi10.1007/s00467-003-1285-z
dc.identifier.eissn1432-198X
dc.identifier.issn0931-041X
dc.identifier.urihttps://doi.org/10.1007/s00467-003-1285-z
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/96481
dc.identifier.wosidWOS:000188455400011
dc.issue.numero1
dc.language.isoen
dc.pagina.final70
dc.pagina.inicio66
dc.revistaPediatric nephrology
dc.rightsacceso restringido
dc.subjectpediatric arterial hypertension
dc.subjectrenovascular hypertension
dc.subjectrenal scintigraphy
dc.subjectcaptopril
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleCaptopril scintigraphy in the study of arterial hypertension in pediatrics
dc.typeartículo
dc.volumen19
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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