Historia natural de la infección por virus de inmunodeficiencia humano en una cohorte de pacientes chilenos

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dc.catalogadoraba
dc.contributor.authorVial Claro, Pablo Agustín
dc.contributor.authorFerreccio Readi, Catterina
dc.contributor.authorAbarca Villaseca, Katia
dc.contributor.authorOrtiz Neira, Marisol Edith
dc.contributor.authorNoriega Ricalde, Miguel Luis
dc.contributor.authorPérez Cortés, Carlos
dc.contributor.authorLabarca L., Jaime
dc.contributor.authorTorres H. M.
dc.contributor.authorFerrés, Marcela
dc.contributor.authorGonzález Wiedmaier, Claudia
dc.contributor.authorAcuña L., Guillermo
dc.date.accessioned2025-04-01T15:31:55Z
dc.date.available2025-04-01T15:31:55Z
dc.date.issued1996
dc.description.abstractWe characterized clinical manifestations and the risk to develop AIDS in a cohort of 32 patients infected with human immunodeficiency virus without AIDS. A multivariate analysis was performed to determine association between the progression of infection and control variables (socioeconomic level, age, sex and sexual preferences) and causal variables (psycho-social changes, significant clinical events, stress scoring and sexual activity). The cumulative AIDS incidence, defined as a CD4 lymphocyte count below 200 cells/cm3 was 50% at 6.5 years and 82% at 8 years. Using clinical criteria to define AIDS, 50% developed the disease at 8 years of follow up. Among studied factors, only age (faster progression at higher age) and time of evolution were associated with progression. In stages before AIDS, the most frequent diseases were acute diarrhea, sexual transmission diseases, oral candidiasis, sinusitis and varicella zoster infections. The reduction of CD4 lymphocytes below 200 cells/cm3 always preceded the symptoms of the disease. Two patients have remained more than eight years without clinical or immunological deterioration.
dc.format.extent11 páginas
dc.fuente.origenORCID
dc.identifier.issn0034-9887
dc.identifier.pubmedid9035503
dc.identifier.scopusid2-s2.0-0030133461
dc.identifier.urihttps://www.scopus.com/record/display.uri?eid=2-s2.0-0030133461&origin=inward&txGid=57eb3a8dd34e49845ebf5c6228299af8
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/103077
dc.identifier.wosidWOS:A1996UY88900001
dc.information.autorucEscuela de Medicina; Vial Claro, Pablo Agustín; S/I; 56396
dc.information.autorucEscuela de Medicina; Ferreccio Readi, Catterina; 0000-0001-6331-5534; 99684
dc.information.autorucEscuela de Medicina; Abarca Villaseca, Katia; 0000-0003-0404-3887; 70281
dc.information.autorucEscuela de Medicina; Noriega Ricalde, Miguel Luis; S/I; 52880
dc.information.autorucEscuela de Medicina; Pérez Cortés, Carlos; S/I; 66650
dc.information.autorucEscuela de Medicina; Labarca L., Jaime; S/I; 62874
dc.information.autorucEscuela de Medicina; Ferrés, Marcela; 0000-0001-9415-4657; 66180
dc.information.autorucEscuela de Medicina; Acuña L., Guillermo; S/I; 99289
dc.issue.numero5
dc.language.isoes
dc.nota.accesocontenido parcial
dc.pagina.final535
dc.pagina.inicio525
dc.revistaRevista Medica de Chile
dc.rightsacceso restringido
dc.subjectAIDS
dc.subjectCohort studies
dc.subjectHIV
dc.subjectHuman immunodeficiency virus
dc.subjectImmune deficiency syndrome
dc.subjectNatural history
dc.subjectPrognosis
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good health and well-being
dc.subject.odspa03 Salud y bienestar
dc.titleHistoria natural de la infección por virus de inmunodeficiencia humano en una cohorte de pacientes chilenos
dc.title.alternativeNatural history of human immunodeficiency virus infection in a cohort of chilean patients
dc.typeartículo de revisión
dc.volumen124
sipa.codpersvinculados56396
sipa.codpersvinculados99684
sipa.codpersvinculados70281
sipa.codpersvinculados52880
sipa.codpersvinculados66650
sipa.codpersvinculados62874
sipa.codpersvinculados66180
sipa.codpersvinculados99289
sipa.trazabilidadORCID;2025-03-03
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