Contemporary management of actinic keratosis
| dc.contributor.author | Navarrete-Dechent, Cristian | |
| dc.contributor.author | Marghoob, Ashfaq A. | |
| dc.contributor.author | Marchetti, Michael A. | |
| dc.date.accessioned | 2025-01-20T23:56:31Z | |
| dc.date.available | 2025-01-20T23:56:31Z | |
| dc.date.issued | 2021 | |
| dc.description.abstract | Actinic keratosis (AK) is a skin lesion characterized by itraepithelial keratinocyte dysplasia and molecular alterations shared with normal chronically sun-damaged skin and squamous cell carcinoma (SCC). AK can undergo spontaneous regression, stable existence, or malignant transformation to cutaneous SCC with progression rates to SCC ranging from 0% to 0.5% per lesion-year and AK spontaneous regression of 15-63%. As AK is a potential precursor of invasive SCC, it is commonly treated to mitigate the risk of malignant progression, including metastasis and death. There is a myriad of available spots (e.g. cryotherapy) and field (e.g. 5-fluorouracil, imiquimod photodynamic therapy) treatments for AK. Recently published randomized clinical trials have helped bridge the gap on AK management. In this viewpoint, we sought to summarize the most up-to-date evidence in the management of AK. | |
| dc.fuente.origen | WOS | |
| dc.identifier.doi | 10.1080/09546634.2019.1682504 | |
| dc.identifier.eissn | 1471-1753 | |
| dc.identifier.issn | 0954-6634 | |
| dc.identifier.uri | https://doi.org/10.1080/09546634.2019.1682504 | |
| dc.identifier.uri | https://repositorio.uc.cl/handle/11534/95159 | |
| dc.identifier.wosid | WOS:000493230500001 | |
| dc.issue.numero | 5 | |
| dc.language.iso | en | |
| dc.pagina.final | 574 | |
| dc.pagina.inicio | 572 | |
| dc.revista | Journal of dermatological treatment | |
| dc.rights | acceso restringido | |
| dc.subject | Actinic keratosis | |
| dc.subject | treatment | |
| dc.subject | squamous cell carcinoma | |
| dc.subject | number needed to treat | |
| dc.subject | randomized controlled trial | |
| dc.subject | evidence | |
| dc.subject | skin cancer | |
| dc.subject | keratinocyte carcinoma | |
| dc.subject | non-melanoma skin cancer | |
| dc.subject.ods | 03 Good Health and Well-being | |
| dc.subject.odspa | 03 Salud y bienestar | |
| dc.title | Contemporary management of actinic keratosis | |
| dc.type | artículo | |
| dc.volumen | 32 | |
| sipa.index | WOS | |
| sipa.trazabilidad | WOS;2025-01-12 |