CHANGES IN NORADRENERGIC VESICLE MARKERS OF RABBIT OVIDUCTS DURING PROGESTERONE TREATMENT

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dc.contributor.authorBELMAR, J
dc.contributor.authorLARA, H
dc.contributor.authorGALLEGUILLOS, X
dc.date.accessioned2025-01-23T19:43:54Z
dc.date.available2025-01-23T19:43:54Z
dc.date.issued1983
dc.description.abstractThe effect of progesterone (P) on norepinephrine (NE), [3H]norepinephrine ([3H]NE) and dopamine .beta.-hydroxylase (DBH) in noradrenergic vesicles from rabbit oviducts was studied after daily injections of the hormone during different periods (4, 7 and 15 days). Progesterone induced a concomitant increase in NE and DBH activity and [3H]NE uptake. To study the mechanism involved in such effects, 4 tissue fractions were obtained by differential centrifugation of the oviducts of which the vesicular fraction was applied over continuous sucrose gradients (0.3-2 M). The changes induced by P in markers of tissue and gradient fractions showed an increase of the NE storage capacity which could be ascribed to an increase in the number of storage vesicles, and/or to a higher extravesicular storage capacity. The occurrence of these mechanisms during pregnancy or after P treatment could account for the (long-lasting) high levels of NE observed in such instances.
dc.fuente.origenWOS
dc.identifier.eissn1529-7268
dc.identifier.issn0006-3363
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/99860
dc.identifier.wosidWOS:A1983RN96600008
dc.issue.numero3
dc.language.isoen
dc.pagina.final604
dc.pagina.inicio594
dc.revistaBiology of reproduction
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleCHANGES IN NORADRENERGIC VESICLE MARKERS OF RABBIT OVIDUCTS DURING PROGESTERONE TREATMENT
dc.typeartículo
dc.volumen29
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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