ENDOCRINE RESPONSE AND OVUM TRANSPORT IN WOMEN TREATED WITH D-TRP6-LUTEINIZING HORMONE-RELEASING HORMONE IN THE POST-OVULATORY PERIOD

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dc.contributor.authorGUILOFF, E
dc.contributor.authorSALVATIERRA, AM
dc.contributor.authorORTIZ, ME
dc.contributor.authorCROXATTO, HB
dc.date.accessioned2025-01-23T19:44:09Z
dc.date.available2025-01-23T19:44:09Z
dc.date.issued1982
dc.description.abstractPossible alterations in ovum transport during increased activity of the hypothalamic-pituitary-ovarian axis were investigated in women. D-Trp6-LHRH, a synthetic peptide with potent gonadotropin-releasing activity, was used to induce a gonadotropin surge and stimulate ovarian steroid secretion in the postovulatory phase. The compound was administered i.m. or i.v. 24, 48 or 72 h following the maximum preovulatory lutropin level in plasma in 7 women. An immediate and pronounced gonadotropin surge accompanied by a moderate increase in the estradiol and progesterone level was obtained in all cases. Ova were recovered from the fallopian tubes in 4 of the 7 women 24 h following treatment. The rate of recovery and the location of ova within the genital tract indicate that the treatment and the resulting endocrine changes failed to accelerate migration of the ova toward the uterus. In comparison with other mammals transport of the ovum in the woman is relatively insensitive to endocrine changes occurring in the postovulatory phase.
dc.fuente.origenWOS
dc.identifier.eissn1097-6868
dc.identifier.issn0002-9378
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/99961
dc.identifier.wosidWOS:A1982MZ06800004
dc.issue.numero2
dc.language.isoen
dc.pagina.final152
dc.pagina.inicio148
dc.revistaAmerican journal of obstetrics and gynecology
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleENDOCRINE RESPONSE AND OVUM TRANSPORT IN WOMEN TREATED WITH D-TRP6-LUTEINIZING HORMONE-RELEASING HORMONE IN THE POST-OVULATORY PERIOD
dc.typeartículo
dc.volumen142
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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