Herpetic Esophagitis and Eosinophilic Esophagitis: A Potential Association

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dc.contributor.authorQuera, Rodrigo
dc.contributor.authorSassaki, Ligia Yukie
dc.contributor.authorNunez, Paulina
dc.contributor.authorContreras, Luis
dc.contributor.authorBay, Constanza
dc.contributor.authorFlores, Lilian
dc.date.accessioned2025-01-20T22:07:36Z
dc.date.available2025-01-20T22:07:36Z
dc.date.issued2021
dc.description.abstractObjective: Rare coexistence of disease or pathology
dc.description.abstractBackground: Gastroesophageal reflux disease, infectious esophagitis, and eosinophilic esophagitis are the most frequent causes of esophagitis, the latter 2 etiologies being generally considered independently. However, the association between both entities has been suggested through case reports in immunocompetent patients.
dc.description.abstractCase Report: We present the case of an immunocompetent 26-year-old man presenting with fever, adynamia, retrosternal pain, and dysphagia. Endoscopy was performed, showing whitish lesions in circular plates with erosions, and in some depressed areas in the middle and distal esophagus. Biopsies showed the presence of ulcerated foci covered by fibrinoleukocyte exudate in granulation tissue and nuclear inclusions with a viral appearance. The immunohistochemical study for herpes simplex virus (HSV) was positive. The patient was treated symptomatically and progressed favorably. The endoscopic control carried out at 3 months showed longitudinal grooves and trachealization, findings compatible with the diagnosis of eosinophilic esophagitis and with biopsies that confirmed the etiology by showing an increase in eosinophil count >20 per field, without isolating HSV.
dc.description.abstractConclusions: This clinical case confirms the possible relationship between esophagitis caused by HSV and eosinophilic esophagitis. Alterations at the immune level and damage to the esophageal mucosa barrier may explain this relationship. In this scenario, an endoscopic follow-up should be considered.
dc.fuente.origenWOS
dc.identifier.doi10.12659/AJCR.933565
dc.identifier.eissn1941-5923
dc.identifier.urihttps://doi.org/10.12659/AJCR.933565
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/94249
dc.identifier.wosidWOS:000702881100001
dc.language.isoen
dc.revistaAmerican journal of case reports
dc.rightsacceso restringido
dc.subjectEosinophilic Esophagitis
dc.subjectEsophagitis
dc.subjectImmunocompetence
dc.subjectKeratitis
dc.subjectHerpetic
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleHerpetic Esophagitis and Eosinophilic Esophagitis: A Potential Association
dc.typeartículo
dc.volumen22
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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