INTRAHEPATIC CHOLESTASIS OF PREGNANCY - A RETROSPECTIVE CASE-CONTROL STUDY OF PERINATAL OUTCOME

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dc.contributor.authorRIOSECO, AJ
dc.contributor.authorIVANKOVIC, MB
dc.contributor.authorMANZUR, A
dc.contributor.authorHAMED, F
dc.contributor.authorKATO, SR
dc.contributor.authorPARER, JT
dc.contributor.authorGERMAIN, AM
dc.date.accessioned2024-01-10T12:06:10Z
dc.date.available2024-01-10T12:06:10Z
dc.date.issued1994
dc.description.abstractOBJECTIVES: Intrahepatic cholestasis of pregnancy has been related to a high frequency of abnormal intrapartum fetal heart rate, amniotic fluid meconium, prematurity, and perinatal mortality. To determine whether these adverse perinatal outcomes could be improved with active intervention, we evaluated our results.
dc.description.abstractSTUDY DESIGN: We report a retrospective case-control study of 320 consecutive patients with intrahepatic cholestasis of pregnancy management with antepartum testing and active intervention over a 2-year period.
dc.description.abstractRESULTS: Our results indicate a higher incidence of meconium staining in amniotic fluid at delivery (25% vs 16%, p < 0.05) and spontaneous preterm delivery (12.1% vs 3.9%, p < 0.05), without an increase in the frequency of abnormal intrapartum fetal heart rate (12% vs 11%, not significant), 5-minute Apgar score < 7 (2.0% vs 1.0%, not significant), or perinatal mortality (18/1000 vs 13/1000, not significant).
dc.description.abstractCONCLUSION: Antenatal testing and timed intervention of patients with intrahepatic cholestasis of pregnancy is associated with a reduction of the previously reported adverse perinatal outcomes.
dc.fechaingreso.objetodigital16-04-2024
dc.format.extent6 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1016/S0002-9378(94)70304-3
dc.identifier.eissn1097-6868
dc.identifier.issn0002-9378
dc.identifier.pubmedidMEDLINE:8141222
dc.identifier.urihttps://doi.org/10.1016/S0002-9378(94)70304-3
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/76125
dc.identifier.wosidWOS:A1994NC56600038
dc.information.autorucMedicina;Germain A;S/I;55575
dc.information.autorucMedicina;Manzur A;S/I;57590
dc.issue.numero3
dc.language.isoen
dc.nota.accesoContenido parcial
dc.pagina.final895
dc.pagina.inicio890
dc.publisherMOSBY-ELSEVIER
dc.revistaAMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
dc.rightsacceso restringido
dc.subjectINTRAHEPATIC CHOLESTASIS OF PREGNANCY
dc.subjectOBSTETRIC CHOLESTASIS
dc.subjectPRETERM LABOR
dc.subjectPERINATAL OUTCOME
dc.subjectOBSTETRIC CHOLESTASIS
dc.subjectFETAL
dc.subjectCHILE
dc.subjectACIDS
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleINTRAHEPATIC CHOLESTASIS OF PREGNANCY - A RETROSPECTIVE CASE-CONTROL STUDY OF PERINATAL OUTCOME
dc.typeartículo
dc.volumen170
sipa.codpersvinculados55575
sipa.codpersvinculados57590
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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