Long-Term Effects of Dietary Olive Oil and Hydrogenated Vegetable Oil on Expression of Lipogenic Genes in Subcutaneous Adipose Tissue of Dairy Cows

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dc.contributor.authorVargas-Bello-Perez, Einar
dc.contributor.authorBionaz, Massimo
dc.contributor.authorSciarresi-Arechabala, Pietro
dc.contributor.authorCancino-Padilla, Nathaly
dc.contributor.authorMorales, Maria Sol
dc.contributor.authorRomero, Jaime
dc.contributor.authorLeskinen, Heidi
dc.contributor.authorGarnsworthy, Philip C.
dc.contributor.authorLoor, Juan J.
dc.date.accessioned2025-01-23T21:11:30Z
dc.date.available2025-01-23T21:11:30Z
dc.date.issued2019
dc.description.abstractThe objective of this study was to characterize the long-term transcriptomic effects of lipogenic genes in subcutaneous adipose tissue (SAT) of dairy cows supplemented with unsaturated (olive oil; OO) and saturated (hydrogenated vegetable oil; HVO) lipids. Cows were fed a control diet with no added lipid, or diets containing OO or HVO (n = 5 cows/group) for 63 days. SAT was obtained from the tail-head area at the onset of the study and after 21, 42, and 63 days of supplementation. Treatments had minor effects on expression of measured genes. Both fat supplements reduced expression of PPARG, HVO decreased transcription of the desaturase FADS2 and lipid droplet formation PLIN2, and OO increased transcription of FABP3. Both lipid treatments decreased expression of the transcription regulator SREBF1 and its chaperone (SCAP) during the first 21 days of treatment. Our data indicated that long-term feeding of OO and HVO have a relatively mild effect on expression of lipogenic genes in SAT of mid-lactating cows.
dc.fuente.origenWOS
dc.identifier.doi10.3390/vetsci6030074
dc.identifier.eissn2306-7381
dc.identifier.urihttps://doi.org/10.3390/vetsci6030074
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/100905
dc.identifier.wosidWOS:000565912800016
dc.issue.numero3
dc.language.isoen
dc.revistaVeterinary sciences
dc.rightsacceso restringido
dc.subjectfat supplementation
dc.subjecttranscriptomics
dc.subjectadipose tissue
dc.subjectlipid metabolism
dc.subjectlipogenic gene expression
dc.subjectdairy cows
dc.subject.ods13 Climate Action
dc.subject.odspa13 Acción por el clima
dc.titleLong-Term Effects of Dietary Olive Oil and Hydrogenated Vegetable Oil on Expression of Lipogenic Genes in Subcutaneous Adipose Tissue of Dairy Cows
dc.typeartículo
dc.volumen6
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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