INSPIRATORY MUSCLE DYSFUNCTION AND UNEXPLAINED DYSPNEA IN SYSTEMIC LUPUS-ERYTHEMATOSUS

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dc.contributor.authorJACOBELLI, S
dc.contributor.authorMORENO, R
dc.contributor.authorMASSARDO, L
dc.contributor.authorRIVERO, S
dc.contributor.authorLISBOA, C
dc.date.accessioned2025-01-23T19:27:11Z
dc.date.available2025-01-23T19:27:11Z
dc.date.issued1985
dc.description.abstractThe role of inspiratory muscle dysfunction in lung volume restriction and unexplained dyspnea was studied in 16 patients with systemic lupus erythematosus [SLE]. Maximal mouth inspiratory pressure (PIM) and maximal transdiaphragmatic pressure (Pdimax) were measured. Pdi and its components were determined during quiet breathing. No significant association was found between the activity of the disease, several serologic markers and the in spiratory muscle dysfunction. No specific anti-skeletal muscle antibody was found in these patients. Significant correlations were found between the degree of dyspnea and PIM (r = 0.69, P < 0.01) and Pdimax (r = -0.75, P < 0.001); however, dyspnea did not correlate with specific lung compliance. Vital capacity correlated significantly with the degree of dyspnea (r = -0.813, P < 0.001) and with Pdimax (r = 0.544, P < 0.05). No correlation was found between vital capacity and specific lung compliance. Inspiratory muscle dysfunction can be an important mechanism in the pathogenesis of the lung volume restriction and dyspnea in patients with SLE.
dc.fuente.origenWOS
dc.identifier.eissn1529-0131
dc.identifier.issn0004-3591
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/99699
dc.identifier.wosidWOS:A1985AMN1700008
dc.issue.numero7
dc.language.isoen
dc.pagina.final788
dc.pagina.inicio781
dc.revistaArthritis and rheumatism
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleINSPIRATORY MUSCLE DYSFUNCTION AND UNEXPLAINED DYSPNEA IN SYSTEMIC LUPUS-ERYTHEMATOSUS
dc.typeartículo
dc.volumen28
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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