Bariatric Surgery in Cirrhotic Patients: a Matched Case-Control Study

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dc.contributor.authorQuezada, Nicolas
dc.contributor.authorMaturana, Gregorio
dc.contributor.authorIrarrazaval, Maria Jesus
dc.contributor.authorMunoz, Rodrigo
dc.contributor.authorMorales, Sebastian
dc.contributor.authorAchurra, Pablo
dc.contributor.authorAzocar, Cristobal
dc.contributor.authorCrovari, Fernando
dc.date.accessioned2025-01-23T19:49:05Z
dc.date.available2025-01-23T19:49:05Z
dc.date.issued2020
dc.description.abstractIntroduction Laparoscopic bariatric surgery (LBS) in liver end-stage organ disease has been proven to improve organ function and patients' symptoms. A series of LBS in patients with cirrhosis have shown good results in weight loss, but increased risk of complications. Current literature is based on clinical series. This paper aims to compare LBS (69% gastric bypass) between patients with cirrhosis and without cirrhosis. Methods We conducted a retrospective 1:3 matched case-control study including bariatric patients with cirrhosis and without cirrhosis. Demographics, operative variables, postoperative complications, long-term weight loss, and comorbidity resolution were compared between groups. Results Sixteen Child A patients were included in the patients with cirrhosis (PC) group and 48 in patients without cirrhosis (control) group. Mean age was 50 years; preoperative BMI was 39 +/- 6.8 kg/m(2). Laparoscopic gastric bypass and laparoscopic sleeve gastrectomy were performed in 69% and 31%, respectively. Follow-up was 81% at 2 years for both groups. PC group had a higher rate of overall (31% vs. 6%;p < 0.05) and severe (Clavien-Dindo >= III; 13% vs. 0%;p = 0.013) complications than that of the control group. Mean %EWL of PC at 2 years of follow-up was 84.9%, without differences compared with that of the control group (83.1%). Comorbidity remission in PC was 14%, 50%, and 85% for hypertension, type 2 diabetes, and dyslipidemia, respectively. Patients without cirrhosis had a higher resolution rate of hypertension (65% vs. 14%,p = 0.03). Conclusion LBS is effective for weight loss and comorbidity resolution in patients with obesity and Child A liver cirrhosis. However, these results are accompanied by significantly increased risk of complications.
dc.fuente.origenWOS
dc.identifier.doi10.1007/s11695-020-04929-y
dc.identifier.eissn1708-0428
dc.identifier.issn0960-8923
dc.identifier.urihttps://doi.org/10.1007/s11695-020-04929-y
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/100479
dc.identifier.wosidWOS:000560888300001
dc.issue.numero12
dc.language.isoen
dc.pagina.final4731
dc.pagina.inicio4724
dc.revistaObesity surgery
dc.rightsacceso restringido
dc.subjectLiver cirrhosis
dc.subjectBariatric surgery
dc.subjectBariatric morbidity
dc.subjectNon-alcoholic steatohepatitis (NASH)
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleBariatric Surgery in Cirrhotic Patients: a Matched Case-Control Study
dc.typeartículo
dc.volumen30
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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