CHANGES OF NOREPINEPHRINE LEVELS, TYROSINE-HYDROXYLASE AND DOPAMINE-BETA-HYDROXYLASE ACTIVITIES AFTER CASTRATION AND TESTOSTERONE TREATMENT IN VAS-DEFERENS OF ADULT-RATS

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dc.contributor.authorBUSTAMANTE, D
dc.contributor.authorLARA, H
dc.contributor.authorBELMAR, J
dc.date.accessioned2025-01-23T19:24:05Z
dc.date.available2025-01-23T19:24:05Z
dc.date.issued1989
dc.description.abstractNorepinephrine levels and tyrosine hydroxylase and dopamine-.beta.-hydroxylase activities have been used to evaluate the effect of castration and testosterone treatment on the sympathetic innervation of the adult was deferens. Castration was followed by a decrease in both norepinephrine content and tyrosine hydroxylase activity, even though the changes were not concomitant. Treatment of castrated animals with testosterone reversed the effect of castration on organ weight and norepinephrine content, but only a short-lasting increase in tyrosine hydroxylase activity occurred at the beginning of testosterone treatments. In contrast, the testosterone-induced recovery of norepinephrine content observed at this time was accompanied by a marked increase in dopamine-.beta.-hydroxylase activity. The results suggest that in rat was deferens, norepinephrine levels are under androgenic control and that this regulation mainly involves changes in dopamine-.beta.-hydroxylase activity rather than a modulation of tyrosine hydroxylase.
dc.fuente.origenWOS
dc.identifier.eissn1529-7268
dc.identifier.issn0006-3363
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/99307
dc.identifier.wosidWOS:A1989U514100014
dc.issue.numero3
dc.language.isoen
dc.pagina.final548
dc.pagina.inicio541
dc.revistaBiology of reproduction
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleCHANGES OF NOREPINEPHRINE LEVELS, TYROSINE-HYDROXYLASE AND DOPAMINE-BETA-HYDROXYLASE ACTIVITIES AFTER CASTRATION AND TESTOSTERONE TREATMENT IN VAS-DEFERENS OF ADULT-RATS
dc.typeartículo
dc.volumen40
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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