Post-suckling prolactin:oestradiol ratio - a potential index to predict the duration of lactational amenorrhoea in women

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dc.contributor.authorCampino, C
dc.contributor.authorAmpuero, S
dc.contributor.authorDiaz, S
dc.contributor.authorLopez, JM
dc.contributor.authorSeronFerre, M
dc.date.accessioned2025-01-21T01:33:14Z
dc.date.available2025-01-21T01:33:14Z
dc.date.issued1997
dc.description.abstractTo assess whether the duration of lactational amenorrhoea can be predicted in individual women, we studied the pre-and post-suckling concentrations of immune prolactin (IR-PRL) and of bioactive prolactin (BIO-PRL) and basal concentrations of oestradiol in ten amenorrhoeic fully nursing women at 3 months post-partum. The women were of similar age, weight and had infants of similar growth rate, Five of these women were to experience long amenorrhoea (>180 days) and the others short amenorrhoea (<180 days), Blood samples were drawn 30 min after a suckling episode initiated at 0800 h, 1600 h and 2400 h. BIO-PRL distinguished between groups of women at 0030 h but not at other times, while there was considerable overlap between values for IR-PRL and oestradiol at all times studied, At 1630 h, the ratios post-suckling BIO-PRL: oestradiol and post-suckling IR-PRL:oestradiol were above 2000 in the women that were to experience long amenorrhoea and below this threshold in the other women, The ratio post-suckling BIO-PRL:oestradiol provided more information since the difference between the lowest ratio in the long amenorrhoea and the highest ratio in the short was 699, while it was 520 for the IR-PRL:oestradiol ratio, The determination of these ratios may help to predict the duration of lactational amenorrhoea in individual fully nursing women.
dc.fuente.origenWOS
dc.identifier.eissn1460-2350
dc.identifier.issn0268-1161
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/97393
dc.identifier.wosidWOS:A1997XV35600012
dc.issue.numero7
dc.language.isoen
dc.pagina.final1426
dc.pagina.inicio1421
dc.revistaHuman reproduction
dc.rightsacceso restringido
dc.subjectlactational amenorrhoea
dc.subjectoestradiol
dc.subjectprolactin
dc.subject.ods03 Good Health and Well-being
dc.subject.ods05 Gender Equality
dc.subject.odspa03 Salud y bienestar
dc.subject.odspa05 Igualdad de género
dc.titlePost-suckling prolactin:oestradiol ratio - a potential index to predict the duration of lactational amenorrhoea in women
dc.typeartículo
dc.volumen12
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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