Impulse oscillometry in preschool children with persistent asthma can predict spirometry at school age

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dc.contributor.authorVidal Grell, Alberto
dc.contributor.authorGonzalez Vera, Ramiro
dc.contributor.authorMendez Yarur, Alejandra
dc.contributor.authorCastro-Rodriguez, Jose A.
dc.contributor.authorPalomino Montenegro, Maria Angelica
dc.contributor.authorFielbaum Colodro, Oscar
dc.contributor.authorAbara Elias, Selim
dc.contributor.authorSaavedra Bentjerodt, Monica
dc.contributor.authorMackenney Poblete, Jorge
dc.date.accessioned2025-01-20T20:17:42Z
dc.date.available2025-01-20T20:17:42Z
dc.date.issued2023
dc.description.abstractBackgroundLung function in children with persistent asthma may be impaired during preschool and school ages. The aim of this study was to describe if some preschool impulse oscillometry (IOS) parameters are related to spirometry alterations on reaching school age. MethodsIn 66 diagnosed with persistent asthma, an IOS was performed at entrance and followed-up to school age where a spirometry was done. ResultsThe mean age was 4.9 years at the first evaluation and 7.9 years at the second evaluation, and 59.1% were male. During preschool, R5, R20, Fres, AX, and D5-20 were found to have diagnostic accuracy (area under the curve > 0.7) for predicting abnormal spirometry during school age (defined as FEV1 and/or FEV/FVC and/or FVC values below the lower limit of normality according to Quanjer predictive values). AX, D5-20, and R5 had the best LR+ to increase the probability of abnormal spirometry (50, 10, and 7.1, respectively). R20, R5, and AX was the best IOS parameters for discriminating bronchodilator response (BDR) in schoolchildren (LR+ = 3.4, 2.9, and 2.8, respectively). ConclusionThe findings of this study indicate that some IOS parameters between 3 and 5 years of age are useful for predicting abnormal spirometry and BDR at school age.
dc.fuente.origenWOS
dc.identifier.doi10.1002/ppul.26333
dc.identifier.eissn1099-0496
dc.identifier.issn8755-6863
dc.identifier.urihttps://doi.org/10.1002/ppul.26333
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/92415
dc.identifier.wosidWOS:000928516100001
dc.issue.numero5
dc.language.isoen
dc.pagina.final1416
dc.pagina.inicio1411
dc.revistaPediatric pulmonology
dc.rightsacceso restringido
dc.subjectasthma
dc.subjectIOS
dc.subjectpreschoolers
dc.subjectpulmonary function testing
dc.subjectschoolchildren
dc.subjectspirometry
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleImpulse oscillometry in preschool children with persistent asthma can predict spirometry at school age
dc.typeartículo
dc.volumen58
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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