EFFECTS OF 6-HYDROXY-DOPAMINE ON CAROTID-BODY CHEMO-SENSORY ACTIVITY

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dc.contributor.authorZUAZO, A
dc.contributor.authorZAPATA, P
dc.date.accessioned2025-01-23T19:44:47Z
dc.date.available2025-01-23T19:44:47Z
dc.date.issued1978
dc.description.abstract6-OH-DA [6-hydroxy-dopamine] HBr (5-25 mg) injected into 1 common carotid artery of pentobarbitone-anesthetized cats, induced a transient inhibition of chemosensory discharges recorded from the ipsilateral carotid nerve, but did not change chemosensory frequency during spontaneous ventilation, periodic deep breaths and asphyxia. Chemosensory activities recorded simultaneously from both carotid nerves showed no differences in their inhibitory responses to dopamine and their excitatory responses to NaCN, up to 48 h after the injections of 6-OH-DA. Apparently 6-OH-DA acts initially as a dopamine analog, and does not impair subsequent carotid body chemoreception or dopamine-induced inhibition, as doses producing abolition of noradrenergic transmission.
dc.fuente.origenWOS
dc.identifier.eissn1872-7972
dc.identifier.issn0304-3940
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/100127
dc.identifier.wosidWOS:A1978FT12600009
dc.issue.numero4
dc.language.isoen
dc.pagina.final328
dc.pagina.inicio323
dc.revistaNeuroscience letters
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleEFFECTS OF 6-HYDROXY-DOPAMINE ON CAROTID-BODY CHEMO-SENSORY ACTIVITY
dc.typeartículo
dc.volumen9
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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