Diagnóstico neuropsicológico diferencial en enfermedad de Alzheimer y demencia frontotemporal: una revisión sistemática cualitativa

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dc.catalogadorjlo
dc.contributor.authorToloza Ramírez, David Isaias
dc.contributor.authorMéndez Orellana, C.
dc.contributor.authorMartella, D.
dc.date.accessioned2026-01-07T12:39:45Z
dc.date.available2026-01-07T12:39:45Z
dc.date.issued2021
dc.description.abstractAlzheimer's disease (AD) has classically been considered to present typical cognitive symptoms and neuroanatomical changes. However, the neurobiological basis of some clinical phenotypes of AD is similar to that of frontotemporal dementia (FTD). Therefore, the heterogeneity of these diseases leads to uncertain evaluation and diagnosis processes, due to limited understanding of the associated neurocognitive symptoms. This systematic review aims to describe neuropsychological characteristics and similarities in patients with AD and FTD, and to identify critical points for their differential diagnosis. Methods: The present study followed the PRISMA guidelines and included studies from the PubMed, Scopus, and Web of Science databases, published between 2005 and 2020. Results: The search returned a total of 41 articles eligible for critical analysis. The available evidence points to key differences in such cognitive domains as language (eg, verbal fluency), memory, social cognition, executive functioning, and behaviour; these should be considered in all neuropsychological assessments and diagnostic processes. Conclusion: Such language domains as verbal fluency (semantic and phonemic) and semantic/grammar alterations seem to be useful markers for differential diagnosis between AD and FTD.
dc.format.extent16 páginas
dc.fuente.origenScopus
dc.identifier.doi10.1016/j.neurop.2021.03.004
dc.identifier.eissn2667-0496
dc.identifier.issn2667-0496
dc.identifier.scopusidSCOPUS_ID:85134132100
dc.identifier.urihttps://doi.org/10.1016/j.neurop.2021.03.004
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/107555
dc.information.autorucDepartamento de Ciencias de la Salud; Mendez Orellana, Carolina Patricia; 0000-0001-5217-9725; 1015155
dc.information.autorucEscuela de Medicina; Toloza Ramírez, David Isaias; S/I; 1186482
dc.issue.numero1
dc.language.isoes
dc.nota.accesocontenido parcial
dc.pagina.final97
dc.pagina.inicio82
dc.revistaNeurology Perspectives
dc.rightsacceso restringido
dc.subjectAlzheimer's disease
dc.subjectDifferential diagnosis
dc.subjectFrontotemporal dementia
dc.subjectNeuropsychological assessment
dc.subject.ddc610
dc.subject.ods03 Good health and well-being
dc.subject.odspa03 Salud y bienestar
dc.titleDiagnóstico neuropsicológico diferencial en enfermedad de Alzheimer y demencia frontotemporal: una revisión sistemática cualitativa
dc.title.alternativeNeuropsychological differential diagnosis of Alzheimer disease and frontotemporal dementia: a qualitative systematic review
dc.typereseña
dc.volumen1
sipa.codpersvinculados1015155
sipa.codpersvinculados1186482
sipa.trazabilidadSCOPUS;10-11-2022
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