MEMBRANE-BOUND FORM OF ACETYLCHOLINESTERASE ACTIVATED DURING POSTNATAL-DEVELOPMENT OF THE RAT SOMATOSENSORY CORTEX

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dc.contributor.authorINESTROSA, NC
dc.contributor.authorRUIZ, G
dc.date.accessioned2025-01-23T19:27:02Z
dc.date.available2025-01-23T19:27:02Z
dc.date.issued1985
dc.description.abstractWe are interested in the expression of synapse-specific macromolecules and its correlation with the appearance of neuronal types and synaptogenesis during development of the mammalian brain. We report here studies showing that the appearance of acetylcholinesterase (AChE) at layer IV of the rat somatosensory cortex is correlated with the expression of a membrane-bound AChE. Both its electrophoretic mobility and its sedimentation coefficient remain unaltered during maturation; however, its kinetics parameters, the heat and fixative sensitivities and the substrate inhibition changed through development. Our results suggest that an adult form of membrane-bound AChE is expressed postnatally.
dc.fuente.origenWOS
dc.identifier.eissn1421-9859
dc.identifier.issn0378-5866
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/99682
dc.identifier.wosidWOS:A1985ARM4800005
dc.issue.numero2
dc.language.isoen
dc.pagina.final132
dc.pagina.inicio120
dc.revistaDevelopmental neuroscience
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleMEMBRANE-BOUND FORM OF ACETYLCHOLINESTERASE ACTIVATED DURING POSTNATAL-DEVELOPMENT OF THE RAT SOMATOSENSORY CORTEX
dc.typeartículo
dc.volumen7
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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