RIBOFLAVIN SENSITIZED PHOTOOXIDATION OF TYROSINE

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dc.contributor.authorSILVA, E
dc.contributor.authorGODOY, J
dc.date.accessioned2024-01-10T12:08:17Z
dc.date.available2024-01-10T12:08:17Z
dc.date.issued1994
dc.description.abstractThe oxygen reactive species generated during the photooxidation of tyrosine sensitized by riboflavin were studied and the products formed were isolated. It was found that this process occurs preferently through a type I mechanism, which involves the direct interaction between the excited state of the sensitizer and tyrosine. The formation of O-2.-, H2O2 and .OH was detected along the photooxidative process. By changing H2O by D2O it could be established that O-1(2) has no significant role in the photooxidation of tyrosine sensitized by riboflavin. When a previously irradiated solution of tyrosine was applied to a Sephadex G-15 column, four fractions could be separated corresponding to products having hydrodynamic volumes larger than those of the reactants. By the use of C-14-tyrosine the aminoacidic origin of the products could be determined; one of them was identified as bityrosine, according to its fluorescence properties and H-1-NMR spectrum.
dc.format.extent4 páginas
dc.fuente.origenWOS
dc.identifier.issn0300-9831
dc.identifier.pubmedidMEDLINE:7883461
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/76376
dc.identifier.wosidWOS:A1994PX89600002
dc.information.autorucQuímica;Silva E;S/I;98771
dc.issue.numero4
dc.language.isoen
dc.nota.accesoSin adjunto
dc.pagina.final256
dc.pagina.inicio253
dc.publisherVERLAG HANS HUBER
dc.revistaINTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH
dc.rightsregistro bibliográfico
dc.subjectRIBOFLAVIN
dc.subjectTYROSINE
dc.subjectPHOTOOXIDATION
dc.subjectBITYROSINE
dc.subjectOXYGEN REACTIVE SPECIES
dc.subjectTRYPTOPHAN
dc.subjectMECHANISM
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleRIBOFLAVIN SENSITIZED PHOTOOXIDATION OF TYROSINE
dc.typeartículo
dc.volumen64
sipa.codpersvinculados98771
sipa.indexWOS
sipa.trazabilidadCarga SIPA;09-01-2024
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