Exactitud diagnóstica de la tomografía computarizada en la estadificación del cáncer de colon

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dc.article.number100714
dc.contributor.authorCarcamo, Leonardo C.
dc.contributor.authorImigo, Felipe
dc.contributor.authorMolina, Maria E.
dc.contributor.authorUrrejola, Gonzalo
dc.contributor.authorHenriquez, Hector
dc.contributor.authorFigueroa, Daniela
dc.contributor.authorSan Martin, Rodrigo
dc.date.accessioned2025-05-01T10:30:37Z
dc.date.available2025-05-01T10:30:37Z
dc.date.issued2022
dc.description.abstract© 2022, Sociedad de Cirujanos de Chile. All rights reserved.Introduction: Neoadjuvant therapy is an emerging treatment for selected cases of colon cancer. The decision is based on the analysis of preoperative images taken by computed tomography. However, its ability to discriminate those who could benefit from this therapy is unknown. Aim: Our objective is to determine the diagnostic accuracy of computed tomography to evaluate the colon cancer stage and its correlation among expert radiologists. Materials and Method: Diagnostic accuracy study. After sample size calculation, we randomly selected 47 patients who underwent a colonic adenocarcinoma resection with curative intent and had available images up to 60 days after surgery. The depth of tumor and lymph nodal invasion were evaluated by two expert radiologists, blinded to each other. The differences between radiologists were audited by a third one. The results were correlated with biopsy as the gold standard. We calculated sensitivity, specificity, negative predictive value, positive predictive value, and diagnostic accuracy of computed tomography. The agreement between radiologists was calculated using the kappa index. Results: The accuracy to differentiate T3-T4 tumors from T1-T2 was 89.4%. In contrast, ability to differentiate T4 tumors from T3 tumors was 65.9%. The accuracy to determine an N (+) was 66%. Agreement between radiologists was 0.929 to identify T1-2, 0.602 for T3, 0.584 for T4 tumors. To determine an N (+), the concordance was 0.521. Conclusion: Diagnostic computed tomography accuracy in colon cancer is adequate to differentiate advanced tumors. However, its ability to discriminate between T3 and T4, N (+) and the low agreement between radiologists suggests the need for complementary imaging techniques.
dc.description.funderCONICYT
dc.description.funderFONDECYT
dc.fechaingreso.objetodigital2025-09-21
dc.format.extent5 páginas
dc.fuente.origenScopus
dc.identifier.doi10.35687/s2452-454920220011162
dc.identifier.eissn2452-4549
dc.identifier.issn2452-4557
dc.identifier.pubmedid34990812
dc.identifier.scopusidSCOPUS_ID:85124815745
dc.identifier.urihttps://doi.org/10.35687/s2452-454920220011162
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/103638
dc.identifier.wosidWOS:000787873200002
dc.information.autorucEscuela de Medicina; Urrejola Schmied Gonzalo Ignacio; S/I; 199958
dc.information.autorucEscuela de Medicina; Molina Pezoa Maria Elena; S/I; 102077
dc.information.autorucEscuela de Medicina; Henriquez Leigthon Hector Sebastian; S/I; 127093
dc.issue.numero1
dc.language.isoes
dc.nota.accesocontenido completo
dc.pagina.final40
dc.pagina.inicio36
dc.revistaRevista de Cirugia
dc.rightsacceso abierto
dc.subjectColon cancer
dc.subjectComputed tomography
dc.subjectDiagnostic accuracy
dc.subjectNeoadjuvant therapy
dc.subject.ddc400
dc.subject.deweyLenguases_ES
dc.subject.ods11 Sustainable cities and communities
dc.subject.odspa11 Ciudades y comunidades sostenibles
dc.titleExactitud diagnóstica de la tomografía computarizada en la estadificación del cáncer de colon
dc.title.alternativeDiagnostic accuracy of computed tomography in colon cancer staging
dc.typeartículo
dc.volumen74
sipa.codpersvinculados199958
sipa.codpersvinculados102077
sipa.codpersvinculados127093
sipa.indexScopus
sipa.trazabilidadCarga WOS-SCOPUS;01-05-2025
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