STURGE-WEBER SYNDROME: CLINICAL AND RADIOLOGICAL CORRELATES IN 86 PATIENTS

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dc.contributor.authorFogarasi, Andras
dc.contributor.authorLoddenkemper, Tobias
dc.contributor.authorMellado, Cecilia
dc.contributor.authorTuxhorn, Ingrid
dc.contributor.authorEvers, Georg
dc.contributor.authorSarco, Dean
dc.contributor.authorBurgess, Richard C.
dc.contributor.authorHalasz, Peter
dc.contributor.authorBarsi, Peter
dc.contributor.authorGyorsok, Zsuzsanna
dc.contributor.authorGyimesi, Csilla
dc.contributor.authorKobor, Jeno
dc.contributor.authorSiegler, Zsuzsanna
dc.contributor.authorJanszky, Jozsef
dc.contributor.authorJakus, Rita
dc.contributor.authorRasonyi, Gyoergy
dc.contributor.authorEbner, Alois
dc.contributor.authorWoermann, Friedrich G.
dc.contributor.authorSahin, Mustafa
dc.date.accessioned2025-01-24T00:04:49Z
dc.date.available2025-01-24T00:04:49Z
dc.date.issued2013
dc.description.abstractBackgrounds and purpose - To correlate the extent of the leptomeningeal angiomatosis with clinical features in Sturge-Weber syndrome (SWS).
dc.description.abstractMethods - The study group consisted of 86 consecutive patients aged two months to 56 (mean 7.9 +/- 10.3) years with SWS and epilepsy. Clinical and MRI data were analyzed.
dc.description.abstractResults - Based on the extent of leptomeningeal angiomatosis, patients were divided into two subgroups: 43 patients had hemispheric angiomatosis and atrophy, whereas, another 43 had focal involvement. Nine of the 43 hemispherial patients (10%) showed bilateral involvement: all of these bilateral cases demonstrated dominance in a single side with hemispheric leptomeningeal angiomatosis and contralateral focal extension.
dc.description.abstractHemispheric and focal subgroups were clinically different. Patients with hemispheric SWS were younger at the age of epilepsy onset (p<0.001) and age at MRI examination (p<0.05). Neither gender, lateralization, duration of epilepsy, appearance of secondarily generalized seizures, nor seizure frequency revealed a significant difference between subgroups.
dc.description.abstractConclusion - Bilateral involvement is frequent and occurs in cases with a hemisperic involvement on one side. The age of epilepsy onset is related to the extent of leptomeningeal angiomatosis. Patients with hemispheric form of SWS presented with earlier age of seizure onset. Focal pial angiomatoses do not tend to progress (a longer duration is not associated with more frequent hemispheric involvement). Other variables including seizure frequency and secondary generalized tonic-clonic seizures are not associated with the extent of angiomatosis.
dc.fuente.origenWOS
dc.identifier.issn0019-1442
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/101813
dc.identifier.wosidWOS:000314669400009
dc.issue.numero1-2
dc.language.isoen
dc.pagina.final57
dc.pagina.inicio53
dc.revistaIdeggyogyaszati szemle-clinical neuroscience
dc.rightsacceso restringido
dc.subjectSturge-Weber syndrome
dc.subjectepilepsy
dc.subjectMRI
dc.subjectage
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleSTURGE-WEBER SYNDROME: CLINICAL AND RADIOLOGICAL CORRELATES IN 86 PATIENTS
dc.typeartículo
dc.volumen66
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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