Reduction in Helicobacter pylori infection among patients referred for upper gastrointestinal endoscopy in Santiago, Chile, between 2010-2020Reducción de la infección por Helicobacter pylori en pacientes derivados a endoscopia digestiva alta en Santiago de Chile entre 2010-2020

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dc.article.number105030
dc.contributor.authorSilva F.
dc.contributor.authorLatorre G.
dc.contributor.authorMedel P.
dc.contributor.authorBustamante M.
dc.contributor.authorMontero I.
dc.contributor.authorRobles C.
dc.contributor.authorDukes E.
dc.contributor.authorMartinez F.
dc.contributor.authorBinder M.V.
dc.contributor.authorUribe J.
dc.contributor.authorReyes D.
dc.contributor.authorBittner M.
dc.contributor.authorSirhan M.
dc.contributor.authorEspinoza M.
dc.contributor.authorFuentes-Lopez E.
dc.contributor.authorCandia R.
dc.contributor.authorAguero C.
dc.contributor.authorVargas J.I.
dc.contributor.authorEspino A.
dc.contributor.authorRiquelme A.
dc.date.accessioned2024-10-15T07:00:10Z
dc.date.available2024-10-15T07:00:10Z
dc.date.issued2024
dc.description.abstractLatin America presents a high prevalence of Helicobacter pylori(Hp) infection. Between1996-2003, the prevalence in Santiago, Chile, was 70%; recent studies indicate a decreasein this infection. Updating the frequency of Hp is crucial due to its associated health impact. OBJECTIVE: Our objective was to describe the trend in Hp infection in patients undergoingambulatory esophagogastroduodenoscopy (EGD) in a Chilean population. MATERIALS AND METHODS: A retrospective observational study was conducted on patients over 18 years old who attended a first EGD with a rapid urease test between 2010-2020. Time trendswere described through time series analysis. A Poisson model was constructed to estimatethe risk of infection, adjusted for age and gender. RESULTS: 11,355 patients were included[66.9% females; mean age 52 years; Hp 41.6%]. Male gender presented a higher frequencyof Hp infection [RR 1.13; (95% CI: 1.08-1.18)].Hp frequency infection decreased significantlyfrom 45.1% in 2010 to 29% in 2020, with a 36% lower probability of Hp infection in 2020 compared to 2010 [RR 0.64;(95% CI: 0.55-0.74)]. A progressive decline in Hp infectiontrend was projected, reaching values close to 25% by year 2025. CONCLUSION: A significantreduction in Hpinfection was observed between 2010-2020. This decrease could be explained by the implementation of public health policies in the last decade associated with socio-sanitary changes.
dc.description.funderCentro de Excelencia Severo Ochoa 2019-2023
dc.description.funderGovernment of Catalonia, Spain
dc.description.funderNational Institute on Alcohol Abuse and Alcoholism
dc.description.funderSpanish Ministry of Science, Innovation and Universities
dc.description.funderFondo Nacional de Desarrollo Científico y Tecnológico
dc.description.funderANID
dc.format.extent559 páginas
dc.fuente.origenScopus
dc.identifier.doi10.47892/rgp.2024.441.1624
dc.identifier.eissn17482801
dc.identifier.issn1609722X
dc.identifier.pubmedid35430032
dc.identifier.scopusidSCOPUS_ID:85192865549
dc.identifier.urihttps://doi.org/10.47892/rgp.2024.441.1624
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/88220
dc.information.autorucFacultad de Medicina; Fuentes Lopez, Eduardo; S/I; 1013849
dc.issue.numero6
dc.language.isoes
dc.nota.accesoContenido completo
dc.pagina.final20
dc.pagina.inicio14
dc.relation.ispartofThe Lancet Gastroenterology and Hepatology
dc.revistaRevista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru
dc.rightsacceso abierto
dc.subject21st century abilities
dc.subjectInformation literacy
dc.subjectPedagogical issues
dc.subjectTeacher professional development
dc.subject.ods03 Good health and well-being
dc.subject.odspa03 Salud y bienestar
dc.titleReduction in Helicobacter pylori infection among patients referred for upper gastrointestinal endoscopy in Santiago, Chile, between 2010-2020Reducción de la infección por Helicobacter pylori en pacientes derivados a endoscopia digestiva alta en Santiago de Chile entre 2010-2020
dc.typeartículo
dc.volumen44
sipa.codpersvinculados1013849
sipa.indexScopus
sipa.trazabilidadCarga WOS-SCOPUS;15-10-2024
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