Mechanical ventilation in the extreme premature newborn, where we are going?

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dc.article.number102546
dc.article.number102546
dc.contributor.authorGonzalez, Alvaro
dc.contributor.authorEstay, Alberto
dc.date.accessioned2025-05-01T10:32:13Z
dc.date.available2025-05-01T10:32:13Z
dc.date.issued2021
dc.description.abstractExtremely preterm infants frequently require mechanical ventilation (MV). In recent years, a wide variety of ventilators have been developed that provide different modes and precise information on the volumes they deliver, allowing health professionals to optimize ventilation and level of support. The objective of this review is to describe different ventilatory practices in preterm infants.
dc.description.abstractThere are many modalities and their clinical utility has not been well evaluated in large controlled studies and various questions remain unresolved. It is clear that they allow optimize and reduce MV duration, which could reduce lung damage. However, their effects on improving outcomes such as bronchopulmonary dysplasia (BPD) and/or death are not so clear. It becomes necessary to have a greater number of controlled studies that provide solid evidence in order to recommend a specific modality.
dc.description.abstractIn our experience, we try to use MV as little as possible by attempting a quick extubation. In these cases we use the synchronized intermitent mechanical ventilation + pressure support (SIMV+VPS) mode. In those sicker and/or smaller infants who we believe will require MV for a longer time, we prefer to use the assist control AC mode. In both situations ideally with the addition of volume guarantee. Once the patient has stabilized and presents spontaneous respiration, extubation should be considered, usually to CPAP, after loading with methylxanthines. Extubation to S-NIPPV can also be considered in centers that have possibilityofsynchronized mode.
dc.description.abstractSince there are several modalities and types of ventilators, it is recommended that within a unit, a selection be made in order for the clinical team to become familiar with their use.
dc.description.funderNational Fund for Scientific and Technological Development (FONDECYT)
dc.description.funderResearch Direction from Universidad Autonoma de Chile (DIUA)
dc.description.funderVicerrectoria Investigacion de Universidad Catolica de Temuco
dc.description.funderResearch Direction from Universidad de La Frontera (DIUFRO)
dc.description.funderFONDEF Idea
dc.description.funderMillennium Institute on Immunology and Immunotherapy (IMII)
dc.description.funderEuropean Research Council (ERC) under the European Union
dc.format.extent8 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.rmclc.2021.10.006
dc.identifier.eisbn978-84-9880-797-4
dc.identifier.eissn0716-8640
dc.identifier.isbn978-3-031-28205-8
dc.identifier.issn0717-7356
dc.identifier.pubmedidMEDLINE:34727504
dc.identifier.scieloidS0718-69242020000300109
dc.identifier.scopusidSCOPUS_ID:66149183263
dc.identifier.urihttps://doi.org/10.1016/j.rmclc.2021.10.006
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/103840
dc.identifier.wosidWOS:000723407900008
dc.information.autorucEscuela de Medicina; Gonzalez Morande Alvaro Jose; 0000-0002-0442-9109; 65603
dc.information.autorucEscuela de Medicina; Estay Navarrete Alberto Santiago; S/I; 116922
dc.issue.numero6
dc.language.isoes
dc.nota.accesoSin adjunto
dc.pagina.final689
dc.pagina.inicio682
dc.publisherPalgrave Macmillan
dc.relation.ispartofCreativity, Innovation, and Change Across Cultures
dc.revistaREVISTA MEDICA CLINICA LAS CONDES
dc.rightsregistro bibliográfico
dc.subjectMechanical Ventilation
dc.subjectPreterm Infants
dc.subjectVolume-Targeted Ventilation
dc.subjectINTERMITTENT MANDATORY VENTILATION
dc.subjectEXTREMELY PRETERM INFANTS
dc.subjectRESPIRATORY-DISTRESS-SYNDROME
dc.subjectCONTROLLED-TRIAL
dc.subjectINSPIRED OXYGEN
dc.subjectPRESSURE
dc.subjectFLUCTUATIONS
dc.subjectEXTUBATION
dc.subjectCROSSOVER
dc.subjectOUTCOMES
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good health and well-being
dc.subject.odspa03 Salud y bienestar
dc.titleMechanical ventilation in the extreme premature newborn, where we are going?
dc.typeartículo
dc.volumen32
sipa.codpersvinculados65603
sipa.codpersvinculados116922
sipa.indexWOS
sipa.trazabilidadCarga WOS-SCOPUS;01-05-2025
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