DOPAMINE-INDUCED VENTILATORY DEPRESSION IN THE RAT, MEDIATED BY CAROTID NERVE AFFERENTS

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dc.contributor.authorCARDENAS, H
dc.contributor.authorZAPATA, P
dc.date.accessioned2025-01-23T19:44:21Z
dc.date.available2025-01-23T19:44:21Z
dc.date.issued1981
dc.description.abstractIn pentobarbitone-anesthetized rats, i.v. injections of dopamine (DA) at 10-8-10-5 g/kg led to transient ventilatory depression, usually not associated with changes in systemic arterial pressure. DA-induced ventilatory depression consisted of decreases in tidal volume and respiratory frequency in 12 rats and in bradypnea without changes in tidal volume in 5 rats. After bilateral section of the carotid nerves, ventilatory responses to DA were abolished or greatly diminished. DA evidently inhibits carotid body chemosensory discharges in the rat. Chemosensory activity may directly affect respiratory frequency.
dc.fuente.origenWOS
dc.identifier.eissn1872-7972
dc.identifier.issn0304-3940
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/100016
dc.identifier.wosidWOS:A1981LV90600006
dc.issue.numero1
dc.language.isoen
dc.pagina.final33
dc.pagina.inicio29
dc.revistaNeuroscience letters
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleDOPAMINE-INDUCED VENTILATORY DEPRESSION IN THE RAT, MEDIATED BY CAROTID NERVE AFFERENTS
dc.typeartículo
dc.volumen24
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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