IMPORTANCE OF UTERINE EXPULSION OF EMBRYOS IN THE INTERCEPTIVE MECHANISM OF POSTCOITAL ESTRADIOL IN RATS

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dc.contributor.authorORTIZ, ME
dc.contributor.authorBASTIAS, G
dc.contributor.authorDARRIGRANDE, O
dc.contributor.authorCROXATTO, HB
dc.date.accessioned2025-01-23T19:22:52Z
dc.date.available2025-01-23T19:22:52Z
dc.date.issued1991
dc.description.abstractThis study compares the interceptive effectiveness of 1-mu-g oestradiol given as a single s.c. injection at 0900 or 1700 hours on Day 1, 2, 3, or 4 of pregnancy in rats. Increasing the interval from ovulation to treatment accelerated the oviducal transport of a larger number of embryos, the majority of which were lost from the genital tract. However, after treatment at 1700 hours on Day 3 the majority of accelerated embryos were retained in the uterus. The number of implanted embryos on Day 14 was equal to the number of eggs remaining in the tract 24 h after treatment. As a consequence, the highest interceptive effectiveness was obtained with treatment given at 1700 hours on Day 2 and at 0900 hours on Day 3 of pregnancy. Accelerated oviducal transport and uterine expulsion of embryos begin to dissociate after Day 2 of pregnancy in the rat. This explains why the most effective treatments to accelerate oviducal transport are not always the most effective to reduce the number of implantations. These data emphasize the importance of retentive and expulsive properties of the uterus for fertility and infertility.
dc.fuente.origenWOS
dc.identifier.issn1031-3613
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/99121
dc.identifier.wosidWOS:A1991FQ35100010
dc.issue.numero3
dc.language.isoen
dc.pagina.final337
dc.pagina.inicio333
dc.revistaReproduction fertility and development
dc.rightsacceso restringido
dc.subjectFEMALE FERTILITY
dc.subjectOVUM TRANSPORT
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleIMPORTANCE OF UTERINE EXPULSION OF EMBRYOS IN THE INTERCEPTIVE MECHANISM OF POSTCOITAL ESTRADIOL IN RATS
dc.typeartículo
dc.volumen3
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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