CALIBERS AND MICROTUBULES OF NERVE-FIBERS - DIFFERENTIAL EFFECT OF UNDERNUTRITION IN DEVELOPING AND ADULT-RATS

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dc.contributor.authorFAUNDEZ, V
dc.contributor.authorCORDERO, ME
dc.contributor.authorROSSO, P
dc.contributor.authorALVAREZ, J
dc.date.accessioned2025-01-23T19:23:19Z
dc.date.available2025-01-23T19:23:19Z
dc.date.issued1990
dc.description.abstractSural nerves of 9-week-old rats undernourished since birth, and of adult rats food-restricted for 27 and 48 days, were studied to explore the effect of severe undernutrition on the caliber and microtubules of axons in growing and non-growing animals. In 9-week-old undernourished rats, the number and caliber of myelinated fibers were normal while the cross-sectional area of non-medullated fibers was 29% smaller than controls. By contrast, in adult undernourished rats the cross-sectional area of myelinated fibers was affected sooner and to a greater extent (-28%) than that of non-medullated fibers (-23%). Regardless of age, in both controls and in undernourished rats non-medullatedfibers of equal caliber had similar microtubular content. The same was found in 3-.mu.m myelinated axons. These findings indicate that food restriction affects proportionately caliber and microtubules of axons. It is proposed that the anatomy of the axon is in a dynamic equilibrium and that microtubules participate in the specification of the axonal caliber.
dc.fuente.origenWOS
dc.identifier.eissn1872-6240
dc.identifier.issn0006-8993
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/99195
dc.identifier.wosidWOS:A1990CR87200002
dc.issue.numero2
dc.language.isoen
dc.pagina.final204
dc.pagina.inicio198
dc.revistaBrain research
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleCALIBERS AND MICROTUBULES OF NERVE-FIBERS - DIFFERENTIAL EFFECT OF UNDERNUTRITION IN DEVELOPING AND ADULT-RATS
dc.typeartículo
dc.volumen509
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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