Recovery of Bioactive Compounds from Pomegranate (<i>Punica granatum</i> L.) Peel Using Pressurized Liquid Extraction

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dc.contributor.authorGarcia, Paula
dc.contributor.authorFredes, Carolina
dc.contributor.authorCea, Ines
dc.contributor.authorLozano-Sanchez, Jesus
dc.contributor.authorJavier Leyva-Jimenez, Francisco
dc.contributor.authorRobert, Paz
dc.contributor.authorVergara, Cristina
dc.contributor.authorJimenez, Paula
dc.date.accessioned2025-01-20T23:52:58Z
dc.date.available2025-01-20T23:52:58Z
dc.date.issued2021
dc.description.abstractPressurized liquid extraction (PLE) is a clean and environmentally friendly alternative for the recovery of bioactive compounds from fruit by-products. Herein we focused on PLE for the extraction of bioactive compounds from pomegranate peel using a combination of pressurized water and ethanol. The main aim was to determine the optimal PLE conditions, i.e., ethanol percentage and process temperature, to obtain a pomegranate peel extract (PPE) with maximum total phenolic content (TPC), punicalagin content, and antimicrobial activity (AMA). The experimental design was conducted using a central composite design with axial points. Response surface methodology was applied to optimize the response variables using the desirability function. Multiple response optimization indicated a process temperature of 200 degrees C and ethanol of 77% as optimal conditions. The TPC and the punicalagin content of PPE-PLE obtained under optimal conditions were 164.3 +/- 10.7 mg GAE/g DW and 17 +/- 3.6 mg/g DW, respectively. Our findings support the efficacy of PLE on TPC recovery but not in punicalagin recovery. The AMA against S. aureus was 14 mm. The efficacy of PPE-PLE in food applications must continue to be studied in order to achieve adequate information on its potential for developing new food additives.
dc.description.funderFONDECYT
dc.fuente.origenWOS
dc.identifier.doi10.3390/foods10020203
dc.identifier.eissn2304-8158
dc.identifier.urihttps://doi.org/10.3390/foods10020203
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/94930
dc.identifier.wosidWOS:000622531500001
dc.issue.numero2
dc.language.isoen
dc.revistaFoods
dc.rightsacceso restringido
dc.subjectpomegranate by-products
dc.subjectpomegranate peel extract
dc.subjectpolyphenols
dc.subjectpunicalagin
dc.subjectantioxidant
dc.subjectRSM
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleRecovery of Bioactive Compounds from Pomegranate (<i>Punica granatum</i> L.) Peel Using Pressurized Liquid Extraction
dc.typeartículo
dc.volumen10
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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