DUAL EFFECTS OF DOPAMINE UPON CHEMOSENSORY RESPONSES TO CYANIDE

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dc.contributor.authorCARDENAS, H
dc.contributor.authorZAPATA, P
dc.date.accessioned2025-01-23T19:44:33Z
dc.date.available2025-01-23T19:44:33Z
dc.date.issued1980
dc.description.abstractChanges in chemosensory responses to i.v. NaCN during i.v. infusions of dopamine (DA) were studied in pentobarbitone-anesthetized cats. After sectioning both carotid nerves, 1 of them was prepared for electrophysiological recordings of its chemosensory impulses. Basal chemosensory activity was maintained at a reduced level during DA infusions at a rate of 10 .mu.g/kg per min. While sensitivity to NaCN was not modified, reactivity to this agent was reduced for low doses, but enhanced for high doses. Chemoreceptor responses to histotoxic hypoxia are evidently rectified by DA. This is discussed in terms of a modulatory role of endogenous DA in the generation of carotid body sensory impulses.
dc.fuente.origenWOS
dc.identifier.eissn1872-7972
dc.identifier.issn0304-3940
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/100071
dc.identifier.wosidWOS:A1980KC75000016
dc.issue.numero3
dc.language.isoen
dc.pagina.final322
dc.pagina.inicio317
dc.revistaNeuroscience letters
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleDUAL EFFECTS OF DOPAMINE UPON CHEMOSENSORY RESPONSES TO CYANIDE
dc.typeartículo
dc.volumen18
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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