Long-term mortality of coronavirus disease 2019 critically ill patients that required percutaneous tracheostomy in Chile: A multicenter cohort study

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dc.article.numbere24-00023
dc.catalogadorpva
dc.contributor.authorUlloa Morrison, Rodrigo
dc.contributor.authorEscalona, José
dc.contributor.authorNavarrete, Pablo
dc.contributor.authorEspinoza, Javiera
dc.contributor.authorBravo Morales, Sebastián Ignacio
dc.contributor.authorPastore Thomson, Antonia
dc.contributor.authorReyes, Sebastián
dc.contributor.authorBozinovic, Milan
dc.contributor.authorAbbott, Francisco
dc.contributor.authorPairumani, Ronald
dc.contributor.authorNoguera, Roselyn
dc.contributor.authorVera Alarcón, María Magdalena
dc.contributor.authorGonzález, Felipe
dc.contributor.authorValle, Felipe
dc.contributor.authorBakker, Jan
dc.contributor.authorBugedo Tarraza, Guillermo
dc.contributor.authorKattan Tala, Eduardo José
dc.date.accessioned2025-04-15T21:24:22Z
dc.date.available2025-04-15T21:24:22Z
dc.date.issued2024
dc.description.abstractBackground: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection leads to mechanical ventilation (MV) in approximately 20% of hospitalized patients. Tracheostomy expedites weaning of respiratory support. Moreover, there is a paucity of data regarding long-term outcomes of tracheostomized coronavirus disease 2019 (COVID-19) patients. The objective of this study was to describe 1-year mortality in a cohort of COVID-19 critically ill patients who required percutaneous tracheostomy in Chile and to assess the impact of age on outcomes. Methods: A multicenter prospective observational study was conducted in 4 hospitals in Chile between March 2020 and July 2021. Patients with confirmed SARS-CoV-2 infection connected to MV and required percutaneous tracheostomy were included. Baseline data, relevant perioperative and long-term outcomes, such as 1-year mortality, MV duration, intensive care unit (ICU), and hospital length of stay were registered. Patients were dichotomized according to age group (< and ≥ 70 years). Univariate and multivariate logistic regressions were performed to identify predictors of 1-year mortality. Results: Of 1319 COVID-19 ventilated critically ill patients, 23% (304) required a percutaneous tracheostomy. One-year mortality of the study group was 25% (20.2%-30.3%). ICU and hospital length of stay (LOS) were of 37 (27-49) and 52 (40-72) days. One-year mortality was higher in patients ≥ 70 years (36.9% vs. 21.2%, P = 0.012). Multivariate analysis confirmed age and baseline sequential organ failure assessment (SOFA) score as independent predictors, while time from intubation to tracheostomy was not. Conclusion: In COVID-19 critically ill patients who required percutaneous tracheostomy in Chile, the 1-year mortality rate was 25%, with a relevant impact of age on outcomes. An appropriate patient selection likely accounted for the low mortality rate. Future studies should confirm these results.
dc.fechaingreso.objetodigital2025-04-15
dc.format.extent7 páginas
dc.fuente.origenORCID
dc.identifier.doi10.1097/jtccm-d-24-00023
dc.identifier.urihttps://doi.org/10.1097/jtccm-d-24-00023
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/103319
dc.information.autorucEscuela de Medicina; Ulloa Morrison, Rodrigo; 0009-0005-5850-0686; 1080280
dc.information.autorucEscuela de Medicina; Bravo Morales, Sebastián Ignacio; 0000-0003-0998-8433; 13431
dc.information.autorucEscuela de Medicina; Pastore Thomson, Antonia; S/I; 234544
dc.information.autorucEscuela de Medicina; Vera Alarcón, María Magdalena; 0000-0002-2969-3408; 226652
dc.information.autorucEscuela de Medicina; Bakker, Jan; 0000-0003-2236-7391; 1044227
dc.information.autorucEscuela de Medicina; Bugedo Tarraza, Guillermo; 0000-0001-7527-6202; 60490
dc.information.autorucEscuela de Medicina; Kattan Tala, Eduardo José; 0000-0002-1997-6893; 172152
dc.issue.numero4
dc.language.isoen
dc.nota.accesocontenido completo
dc.publisherWolters Kluwer Health, Inc.
dc.revistaJournal of Translational Critical Care Medicine
dc.rightsacceso abierto
dc.rights.licenseAttribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.en
dc.subjectTracheostomy
dc.subjectWeaning
dc.subjectMechanical ventilation
dc.subjectSevere acute respiratory syndrome coronavirus 2
dc.subjectIntensive care
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good health and well-being
dc.subject.odspa03 Salud y bienestar
dc.titleLong-term mortality of coronavirus disease 2019 critically ill patients that required percutaneous tracheostomy in Chile: A multicenter cohort study
dc.typeartículo
dc.volumen6
sipa.codpersvinculados1080280
sipa.codpersvinculados13431
sipa.codpersvinculados234544
sipa.codpersvinculados226652
sipa.codpersvinculados1044227
sipa.codpersvinculados60490
sipa.codpersvinculados172152
sipa.trazabilidadORCID;2025-03-03
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