NEUROTRANSMITTER-RELATED ENZYME ACETYLCHOLINESTERASE IN JUVENILES OF CONCHOLEPAS-CONCHOLEPAS (MOLLUSCA, GASTROPODA, MURICIDAE)

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dc.contributor.authorGONZALEZ, M
dc.contributor.authorPERELMAN, A
dc.contributor.authorFUENTES, ME
dc.contributor.authorCASTILLA, JC
dc.contributor.authorLABARCA, R
dc.contributor.authorBRANDAN, E
dc.contributor.authorGONZALEZPLAZA, R
dc.contributor.authorINESTROSA, NC
dc.date.accessioned2025-01-23T19:23:09Z
dc.date.available2025-01-23T19:23:09Z
dc.date.issued1990
dc.description.abstractWith the aim of understanding the organization of the nervous systemn in the Prosobranchia gastropod Concholepas concholepas, we studied the properties, specificity, sedimentation coefficient, and solubility of the cholinergic enzyme, acetylcholinesterase (AChE). It was found that 95% of the esterase was inhibited by BW284c51 dibromide but not by iso-OMPA, which is consistent with the specificity of AChE. The calculated Km 0.22 mM is eight to ten times higher than are the Kms for AChE of other invertebrates and similar to the values reported for fish and vertebrates. The AChE shows a maximal activity around 22.degree. C, has a glycoprotein character and presents sedimentation coefficients of 6.5 S and 10.5 S. Most of this AChE activity is soluble under low ionic strength conditions; however, the enzyme aggregates in the absence of detergents. In conclusion, our evidence indicates the presence of a well-recognized molecular marker that could be useful for the study of the development of Concholepas concholepas.
dc.fuente.origenWOS
dc.identifier.issn0022-104X
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/99169
dc.identifier.wosidWOS:A1990DP49800001
dc.issue.numero1
dc.language.isoen
dc.pagina.final8
dc.pagina.inicio1
dc.revistaJournal of experimental zoology
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleNEUROTRANSMITTER-RELATED ENZYME ACETYLCHOLINESTERASE IN JUVENILES OF CONCHOLEPAS-CONCHOLEPAS (MOLLUSCA, GASTROPODA, MURICIDAE)
dc.typeartículo
dc.volumen255
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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