Bio-tribological characterization of additives in synovial fluid - usage of graphene, Ti3C2Tx and their synergistic effects

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dc.article.number104955
dc.article.number104955
dc.catalogadorjlo
dc.contributor.authorRamteke R., Sangharatna Munneshwar
dc.contributor.authorUgarte Muñoz, Alfonso E.
dc.contributor.authorZambrano, Dario F.
dc.contributor.authorRamos Grez, Jorge
dc.contributor.authorRosenkranz, Andreas
dc.contributor.authorMarian, Max
dc.date.accessioned2025-09-02T20:02:58Z
dc.date.available2025-09-02T20:02:58Z
dc.date.issued2025
dc.description.abstractSynovial joints play a crucial role in limb biomechanics, depending on advanced lubrication systems to reduce wear. However, disruptions caused by injury or disease often led to the need for joint replacements. Although additive manufacturing enables the production of customized implants, achieving optimal wear resistance is still a significant challenge. This research explores the use of nano-additives in synovial fluid (SF). In this context, we examine the dispersion stability, surface wettability, dynamic viscosity, and bio-tribological behavior of SF enhanced by graphene (G), MXene (Ti3C2Tx), and their hybrid (G-Ti3C2Tx) in the concentrations of 0.5, 2, and 10 mg/mL, respectively. Results show that G and the hybrid maintained stable dispersions in SF, while Ti3C2Tx shows slight sedimentation at lower concentrations. Both G and Ti3C2Tx substantially improved wettability, with the most pronounced effect observed at 10 mg/mL for Ti3C2Tx (29.8 % reduction in contact angle). The bio-tribological analysis indicates that the hybrids induced a superior wear resistance (78.3 % wear reduction at 2 mg/mL). These findings highlight the potential of hybrid, in enhancing the bio-tribological properties of SFs, which is highly prospective to enhance knee prostheses and arthritis management.
dc.description.funderSchaeffler FAG Foundation
dc.description.funderWorld Medical Association
dc.description.funderANID-Chile
dc.description.funderFondequip
dc.description.funderPontificia Universidad Católica de Chile
dc.description.funderFondecyt de Postdoctorado
dc.description.funderFondecyt
dc.format.extent12 páginas
dc.fuente.origenSCOPUS
dc.identifier.doi10.1016/j.rineng.2025.104955
dc.identifier.issn2590-1230
dc.identifier.scopusidSCOPUS_ID:105002763078
dc.identifier.urihttps://doi.org/10.1016/j.rineng.2025.104955
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/105524
dc.identifier.wosidWOS:001476005000001
dc.information.autorucEscuela de Ingeniería; Ramteke R., Sangharatna Munneshwar; S/I; 1315678
dc.information.autorucEscuela de Ingeniería; Ramos Grez, Jorge; 0000-0002-9293-3275; 81538
dc.information.autorucEscuela de Ingeniería; Marian, Max; 0000-0003-2045-6649; 1247429
dc.language.isoen
dc.nota.accesocontenido parcial
dc.revistaResults in Engineering
dc.rightsacceso restringido
dc.subject2D materials
dc.subjectAdditive manufacturing
dc.subjectBio-tribology
dc.subjectHybrid nanomaterials
dc.subjectMXenes
dc.subjectVisco-supplements
dc.subject.ddc620
dc.subject.deweyIngenieríaes_ES
dc.titleBio-tribological characterization of additives in synovial fluid - usage of graphene, Ti3C2Tx and their synergistic effects
dc.typeartículo
dc.volumen26
sipa.codpersvinculados1315678
sipa.codpersvinculados81538
sipa.codpersvinculados1247429
sipa.trazabilidadSCOPUS;2025-04-27
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