Serologically Confirmed Human Leptospirosis in Colombia, 2015–2020

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dc.catalogadorgjm
dc.contributor.authorParra Barrera, Eliana Liseth
dc.contributor.authorBello-Piruccini, Solmara
dc.contributor.authorRodriguez, Karina
dc.contributor.authorDuarte-Valderrama, Carolina
dc.contributor.authorTorres Hidalgo, Marisa
dc.contributor.authorUndurraga Fourcade, Eduardo Andrés
dc.date.accessioned2024-11-25T19:16:56Z
dc.date.available2024-11-25T19:16:56Z
dc.date.issued2024
dc.description.abstractLeptospirosis, a bacterial infection transmitted through contact with infected animals or contaminated water sources, imposes a substantial health burden in Colombia. Since 2007, the National Institute of Health (INS) has mandated the notification and confirmation of all suspected leptospirosis cases. This passive surveillance program employs the microscopic agglutination test (MAT) on serum samples to ascertain confirmed cases of leptospirosis infection. However, the absence of a robust surveillance system has hindered our comprehensive understanding of the morbidity, mortality, geographical distribution, species/serovars, and strains responsible for severe disease. Our study aimed to provide an epidemiological overview of MAT-confirmed human leptospirosis cases reported over 6 years (2015–2020) in Colombia. In addition, we offer insights into the status of leptospirosis in the country, focusing on risk factors and proposing potential improvements for diagnosis and disease management. During the 6-year surveillance period, the laboratory at the INS received 3,535 serum samples from suspected human leptospirosis cases, with 880 (25%) confirmed through MAT. The incidence of leptospirosis was calculated at 1.9 cases per 100,000 people, with a higher prevalence among men (82.1%). Furthermore, 54 (6.1%) deaths were confirmed as leptospirosis, and cases were documented across nearly all regions of Colombia. Our findings emphasize the urgent need to strengthen leptospirosis laboratory surveillance, implement effective prevention measures, and enhance diagnostic capabilities in Colombia. The analysis conducted in this study provides the groundwork for estimating the impact of leptospirosis and raises awareness of its significance in public health.
dc.description.funderAgencia Nacional de Investigación y Desarrollo ANID
dc.description.funderPontificia Universidad Católica de Chile
dc.description.funderCanadian Institute for Advanced Research CIFAR
dc.description.funderFONDAP
dc.description.funderFondo Nacional de Desarrollo Científico y Tecnológico FONDECYT
dc.format.extent9 páginas
dc.fuente.origenSCOPUS
dc.identifier.doi10.4269/ajtmh.23-0654
dc.identifier.issn1476-1645
dc.identifier.scopusidSCOPUS_ID:85205604186
dc.identifier.urihttps://doi.org/10.4269/ajtmh.23-0654
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/88676
dc.information.autorucEscuela de Medicina; Parra Barrera, Eliana Liseth; S/I; 1139372
dc.information.autorucEscuela de Medicina; Torres Hidalgo, Marisa; 0000-0002-9027-8828; 71397
dc.information.autorucEscuela de Ingeniería; Undurraga Fourcade, Eduardo Andrés; 0000-0002-4425-1253; 12868
dc.issue.numero4
dc.language.isoen
dc.nota.accesocontenido parcial
dc.pagina.final864
dc.pagina.inicio856
dc.publisherAmerican Society of Tropical Medicine and Hygiene
dc.revistaAmerican Journal of Tropical Medicine and Hygiene
dc.rightsacceso restringido
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.titleSerologically Confirmed Human Leptospirosis in Colombia, 2015–2020
dc.typeartículo
dc.volumen111
sipa.codpersvinculados1139372
sipa.codpersvinculados71397
sipa.codpersvinculados12868
sipa.trazabilidadSCOPUS;2024-10-27
sipa.trazabilidadORCID;2024-11-25
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