Microbial Regulation of Vitamin D Linked to Colorectal Cancer: A Sex Bias

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dc.catalogadordfo
dc.contributor.authorRiquelme Sánchez, Erick Marcelo
dc.contributor.authorHowell, R.M.
dc.contributor.authorMcAllister, F.
dc.date.accessioned2024-07-18T13:42:20Z
dc.date.available2024-07-18T13:42:20Z
dc.date.issued2023
dc.description.abstractIn a recent issue of Cancer Cell, Li and colleagues revealed that Carnobacterium maltaromaticum (C. maltaromaticum) was significantly depleted in the stool samples of patients with colorectal cancer in a female-specific manner. C. maltaromaticum actively participated in the generation of vitamin D intermediary metabolites, which together with Faecalibacterium prausnitzii and Lachnispiraceae bacterium produce an active metabolite of vitamin D that protects against colorectal cancer development. C. maltaromaticum supplementation induced in a female-specific manner an increase in vitamin D levels that would activate its receptor in the colonic epithelium, protecting against the development of colorectal cancer.
dc.fechaingreso.objetodigital2024-09-02
dc.fuente.origenScopus
dc.identifier.doi10.1158/0008-5472.CAN-23-3128
dc.identifier.issn0008-5472
dc.identifier.scopusidSCOPUS_ID:85177075707
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/87101
dc.identifier.wosidWOS:001126715600002
dc.information.autorucEscuela de Medicina; Riquelme Sanchez Erick Marcelo; 0000-0002-2696-7995; 1001194
dc.issue.numero22
dc.language.isoen
dc.nota.accesoContenido parcial
dc.pagina.final3672
dc.pagina.inicio3670
dc.revistaCancer Research
dc.rightsacceso restringido
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good health and well-being
dc.subject.odspa03 Salud y bienestar
dc.titleMicrobial Regulation of Vitamin D Linked to Colorectal Cancer: A Sex Bias
dc.typeartículo
dc.volumen83
sipa.codpersvinculados1001194
sipa.trazabilidadSCOPUS;2023-12-03
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