Host components that modulate the disease caused by hmpv

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dc.catalogadorjwg
dc.contributor.authorGálvez Arriagada, Nicolás Marcelo Salvador
dc.contributor.authorAndrade Parra, Catalina Andrea
dc.contributor.authorPacheco Ruidiaz, Gaspar Andrés
dc.contributor.authorSoto Ramírez, Jorge Andrés
dc.contributor.authorStranger Mac-kinnon, Vicente
dc.contributor.authorRivera, Tomás
dc.contributor.authorVásquez A.E.
dc.contributor.authorKalergis Parra, Alexis Mikes
dc.date.accessioned2024-01-30T20:16:40Z
dc.date.available2024-01-30T20:16:40Z
dc.date.issued2021
dc.description.abstract© 2021 by the authors. Licensee MDPI, Basel, Switzerland.Human metapneumovirus (hMPV) is one of the main pathogens responsible for acute respiratory infections in children up to 5 years of age, contributing substantially to health bur-den. The worldwide economic and social impact of this virus is significant and must be addressed. The structural components of hMPV (either proteins or genetic material) can be detected by several receptors expressed by host cells through the engagement of pattern recognition receptors. The recognition of the structural components of hMPV can promote the signaling of the immune response to clear the infection, leading to the activation of several pathways, such as those related to the interferon response. Even so, several intrinsic factors are capable of modulating the immune response or directly inhibiting the replication of hMPV. This article will discuss the current knowledge regarding the innate and adaptive immune response during hMPV infections. Accordingly, the host intrinsic components capable of modulating the immune response and the elements capable of restricting viral replication during hMPV infections will be examined.
dc.description.funderDepartment of Microbiology and Immunology of the University of Iowa
dc.description.funderCORFO
dc.description.funderCONICYT
dc.description.funderFONDECYT
dc.fechaingreso.objetodigital2024-05-06
dc.fuente.origenScopus
dc.identifier.doi10.3390/v13030519
dc.identifier.eissn19994915
dc.identifier.issn19994915
dc.identifier.pubmedidMEDLINE:33809875
dc.identifier.scopusidSCOPUS_ID:85103862343
dc.identifier.urihttps://www.mdpi.com/1999-4915/13/3/519/pdf
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/81084
dc.identifier.wosidWOS:000634204500001
dc.information.autorucFacultad de Ciencias Biológicas; Galvez Arriagada Nicolas Marcelo Salvador; 0000-0003-2046-7882; 215440
dc.information.autorucFacultad de Ciencias Biológicas; Andrade Parra Catalina Andrea; ; 234276
dc.information.autorucFacultad de Ciencias Biológicas; Pacheco Ruidiaz Gaspar Andres; ; 1047198
dc.information.autorucFacultad de Ciencias Biológicas; Soto Ramirez Jorge Andres; 0000-0003-0335-9759; 237269
dc.information.autorucPrograma de Estudios Generales College; Stranger Mac-kinnon Vicente; ; 1046190
dc.information.autorucFacultad de Ciencias Biológicas; Kalergis Parra Alexis Mikes; 0000-0001-7622-5263; 90610
dc.issue.numero519
dc.language.isoen
dc.nota.accesoContenido completo
dc.publisherMDPI AG
dc.revistaViruses
dc.rightsacceso abierto
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleHost components that modulate the disease caused by hmpv
dc.typeartículo
dc.volumen13
sipa.codpersvinculados215440
sipa.codpersvinculados234276
sipa.codpersvinculados1047198
sipa.codpersvinculados237269
sipa.codpersvinculados1046190
sipa.codpersvinculados90610
sipa.trazabilidadORCID;2024-01-15
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