The future of MRI in thoracic aortopathy: blueprint for the paradigm shift to improve management

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dc.catalogadordfo
dc.contributor.authorNadel, James
dc.contributor.authorRodríguez Palomares, José
dc.contributor.authorPhinikaridou, Alkystis
dc.contributor.authorPrieto Vásquez, Claudia Del Carmen
dc.contributor.authorMasci, Pier Giorgio
dc.contributor.authorBotnar, René Michael
dc.date.accessioned2025-03-17T13:39:15Z
dc.date.available2025-03-17T13:39:15Z
dc.date.issued2025
dc.description.abstractThoracic aortopathies result in aneurysmal expansion of the aorta that can lead to rapidly fatal aortic dissection or rupture. Despite the availability of abundant non-invasive imaging tools, the greatest contemporary challenge in the management of thoracic aortic aneurysm (TAA) is the lack of reliable metrics for risk stratification, with absolute aortic diameter, growth rate and syndromic factors remaining the primary determinants by which prophylactic surgical intervention is adjudged. Advanced MRI techniques present as a potential key to unlocking insights into TAA that could guide disease surveillance and surgical intervention. MRI has the capacity to encapsulate the aorta as a complex biomechanical structure, permitting the determination of aortic volume, morphology, composition, distensibility and fluid dynamics in a time-efficient manner. Nevertheless, current standard-of-care imaging protocols do not harness its full capacity. This state-of-the-art review explores the emerging role of MRI in the assessment of TAA and presents a blueprint for the required paradigm shift away from aortic size as the sole metric for risk stratifying TAA.
dc.format.extent26 páginas
dc.fuente.origenORCID
dc.identifier.doi10.1016/j.jocmr.2025.101865
dc.identifier.issn1532-429X
dc.identifier.urihttps://doi.org/10.1016/j.jocmr.2025.101865
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/102651
dc.information.autorucEscuela de Ingeniería; Prieto Vasquez Claudia Del Carmen; 0000-0003-4602-2523; 14195
dc.information.autorucEscuela de Ingeniería; Botnar Rene Michael; 0000-0003-2811-2509; 1015313
dc.language.isoen
dc.nota.accesoContenido parcial
dc.revistaJournal of Cardiovascular Magnetic Resonance
dc.rightsacceso restringido
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good health and well-being
dc.subject.odspa03 Salud y bienestar
dc.titleThe future of MRI in thoracic aortopathy: blueprint for the paradigm shift to improve management
dc.typepreprint
sipa.codpersvinculados14195
sipa.codpersvinculados1015313
sipa.trazabilidadORCID;2025-03-03
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