Vegetarians and cardiovascular risk factors

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dc.contributor.authorMezzano, D
dc.contributor.authorMuñoz, X
dc.contributor.authorMartínez, C
dc.contributor.authorCuevas, A
dc.contributor.authorPanes, O
dc.contributor.authorAranda, E
dc.contributor.authorGuasch, V
dc.contributor.authorStrobel, P
dc.contributor.authorMuñoz, B
dc.contributor.authorRodríguez, S
dc.contributor.authorPereira, J
dc.contributor.authorLeighton, F
dc.date.accessioned2025-01-21T01:32:02Z
dc.date.available2025-01-21T01:32:02Z
dc.date.issued1999
dc.description.abstractWe studied hemostatic and inflammatory cardiovascular risk factors (CVRF), and total plasma homocysteine (tHcy) in 26 vegetarians (23 lacto- or ovolactovegetarians and 3 vegans), matched by age, sex and socioeconomic status with omnivorous controls. Vegetarians had significantly lower proportion of eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids in plasma lipids, significantly shortened bleeding time, and increased blood platelet count and in vitro platelet function (aggregation and secretion). Plasma levels of all coagulation or fibrinolytic factors and natural inhibitors synthesized in the liver were lowa in vegetarians than in controls. Whereas for some factors this decrease was statistically significant (fibrinogen, factor VIIc, antithrombin III, protein S, plasminogen) for the remaining (factors VIIIc, Vc, prothrombin, protein C) a trend in the same direction was found. For hemostatic proteins of predominantly extrahepatic origin (von Willebrand factor, tPA, PAI-1) this tendency was not present. No significant differences in inflammatory proteins (C-reactive protein and al-protease inhibitor) were detected in both groups. tHcy was significantly increased in vegetarians, and correlated only with cobalamin levels. The increased platelet function and tHcy found in vegetarians may counteract the known cardiovascular health benefits of vegetarian diet (VD).
dc.fuente.origenWOS
dc.identifier.issn0340-6245
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/97191
dc.identifier.wosidWOS:000080912000015
dc.issue.numero6
dc.language.isoen
dc.pagina.final917
dc.pagina.inicio913
dc.revistaThrombosis and haemostasis
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleVegetarians and cardiovascular risk factors
dc.typeartículo
dc.volumen81
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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