Staging System Performance and Clinical Outcomes for Cutaneous Squamous Cell Carcinoma of the Ear: A Single-Center Retrospective Study

Simple item page
dc.contributor.authorNavarrete-Dechent, Cristian
dc.contributor.authorMori, Shoko
dc.contributor.authorConnolly, Karen
dc.contributor.authorShah, Kalee
dc.contributor.authorDusza, Stephen W.
dc.contributor.authorRossi, Anthony M.
dc.contributor.authorLee, Erica H. H.
dc.contributor.authorBusam, Klaus J.
dc.contributor.authorNehal, Kishwer S.
dc.date.accessioned2025-01-20T20:08:08Z
dc.date.available2025-01-20T20:08:08Z
dc.date.issued2023
dc.description.abstractBACKGROUNDCutaneous squamous cell carcinoma (cSCC) of the ear is associated with poor outcomes. No studies have evaluated current staging system performance in this specific location.OBJECTIVEDescribe clinicopathologic characteristics and outcomes of ear cSCC and evaluate the performance of current staging systems.METHODSRetrospective study including cases diagnosed and treated at a cancer center from January 2000 to December 2014. Demographic, clinical, and pathologic data were collected from clinical records. Biopsy slides were rereviewed and patients were staged according to the American Joint Committee on Cancer (AJCC) seventh, eighth, and Brigham Women's Hospital (BWH) staging.RESULTSOf 125 patients, the mean age at diagnosis was 71.9 years (SD 12.5), with most men (89.6%, n = 112). Median follow-up was 22.3 months. Local recurrence and survival risk factors were similar to cSCC outside the ear. The Akaike's Information Criterion (AIC) estimates showed that the BWH system better predicted outcomes than the AJCC seventh, and the AJCC eighth, with AIC values of 189.9, 270.5, and 274.1, respectively. Limitations of the study include retrospective design, single center study, and no control group.CONCLUSIONCurrent staging systems perform well at stratifying risk in ear cSCC.
dc.fuente.origenWOS
dc.identifier.doi10.1097/DSS.0000000000003842
dc.identifier.eissn1524-4725
dc.identifier.issn1076-0512
dc.identifier.urihttps://doi.org/10.1097/DSS.0000000000003842
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/91872
dc.identifier.wosidWOS:001040734000004
dc.issue.numero8
dc.language.isoen
dc.pagina.final754
dc.pagina.inicio747
dc.revistaDermatologic surgery
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleStaging System Performance and Clinical Outcomes for Cutaneous Squamous Cell Carcinoma of the Ear: A Single-Center Retrospective Study
dc.typeartículo
dc.volumen49
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
Files
Collections
Artículos de revistas