SUBCELLULAR HYPOTHALAMIC FRACTIONS ACTIVE ON OVULATION AND LUTEINIZING-HORMONE RELEASE IN RAT

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dc.contributor.authorFORCELLEDO, ML
dc.contributor.authorLASTRA, MDL
dc.date.accessioned2025-01-23T19:44:57Z
dc.date.available2025-01-23T19:44:57Z
dc.date.issued1977
dc.description.abstractNuclear, microsomal and cytosol fractions were obtained from hypothalamic cells by differential centrifugation in sucrose solutions of different molarities. The nuclear fraction (NF) from immature female rats had an inhibitory effect on ovulation induced with pregnant mare''s serum (PMS) in immature rats and with luteinizing hormone (LH) in chlorpromazine (CPZ)-treated proestrous rats. The microsomal fraction from the same rats increased both types of ovulation. Nuclear and microsomal fractions obtained from immature male rats were inactive on ovulation. Cytosol fractions were inactive. NF active to inhibit ovulation significantly reduced the release of LH induced with synthetic LH-RH in immature male rats and in chronically castrated male rats primed with testosterone (T).
dc.fuente.origenWOS
dc.identifier.eissn1423-0194
dc.identifier.issn0028-3835
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/100168
dc.identifier.wosidWOS:A1977EL95600005
dc.issue.numero1
dc.language.isoen
dc.pagina.final54
dc.pagina.inicio45
dc.revistaNeuroendocrinology
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleSUBCELLULAR HYPOTHALAMIC FRACTIONS ACTIVE ON OVULATION AND LUTEINIZING-HORMONE RELEASE IN RAT
dc.typeartículo
dc.volumen24
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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