Impact of COVID-19 Pandemic on Stroke Severity and Mortality in the South-East of Santiago, Chile

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dc.contributor.authorSilva-Pozo, Andres
dc.contributor.authorVallejos, Jose
dc.contributor.authorAlmeida, Juan
dc.contributor.authorMartoni, Mariano
dc.contributor.authorUribe-San Martin, Reinaldo
dc.contributor.authorMiranda, Maria
dc.contributor.authorDiaz, Pablo
dc.contributor.authorGarcia, Dominga
dc.contributor.authorNavia, Victor
dc.date.accessioned2025-01-20T22:06:52Z
dc.date.available2025-01-20T22:06:52Z
dc.date.issued2021
dc.description.abstractBackground and purpose; Chile has been one of the most affected countries by the COVID-19 pandemic, with one of the highest case rates per population. This has affected the epidemiological behaviour of various pathologies. We analyze the impact of the pandemic on the number of admissions due to stroke, its severity and mortality in Santiago, Chile. Methods: a multicenter observational study based on the records of the 3 hospitals of the South East health service in Santiago, Chile. We recorded the number of patients admitted for ischemic stroke between 01 January 2020 and 30 June 2020. We grouped the cases into two periods, pre-pandemic and pandemic, according to the setting of the state of emergency in Chile. Results: 431 patients were admitted with ischemic stroke during the study period. There was a non -significant decrease in weekly admissions (17 vs 15 patients per week). No differences were observed in the proportion of patients with medical treatment (p = 0.810), IVT (p = 0.638), EVT (p = 0.503) or IVT + EVT (p = 0.501). There was a statistically significant increase in the NIHSS on admission (7.23 vs 8.78, p = 0.009) and mortality (5.2% vs 12.4%, p = 0.012). In a multivariate analysis the NIHSS on admission was associated with the increased mortality (RR 1.11, CI 1.04-1.19, p = 0.003). Conclusion: We found an increase in the severity of ischemic stroke on admission and in-hospital mortality during the pandemic period. The main factor to increase in-hospital mortality was the NIHSS on admission. (c) 2021 Elsevier Inc. All rights reserved.
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.jstrokecerebrovasdis.2021.105953
dc.identifier.eissn1532-8511
dc.identifier.issn1052-3057
dc.identifier.urihttps://doi.org/10.1016/j.jstrokecerebrovasdis.2021.105953
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/94224
dc.identifier.wosidWOS:000704379900011
dc.issue.numero11
dc.language.isoen
dc.revistaJournal of stroke & cerebrovascular diseases
dc.rightsacceso restringido
dc.subjectCOVID-19
dc.subjectStroke
dc.subjectMortality
dc.subjectLatin America
dc.titleImpact of COVID-19 Pandemic on Stroke Severity and Mortality in the South-East of Santiago, Chile
dc.typeartículo
dc.volumen30
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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