Thalidomide for the treatment of metastatic hepatic epithelioid hemangioendothelioma: A case report with a long term follow-up

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dc.contributor.authorSalech, Felipe
dc.contributor.authorValderrama, Sebastian
dc.contributor.authorNervi, Bruno
dc.contributor.authorRodriguez, Juan Carlos
dc.contributor.authorOksenberg, Danny
dc.contributor.authorKoch, Alvaro
dc.contributor.authorSmok, Gladys
dc.contributor.authorDuarte, Ignacio
dc.contributor.authorPerez Ayuso, Rosa Maria
dc.contributor.authorJarufe, Nicolas
dc.contributor.authorMartinez, Jorge
dc.contributor.authorSoza, Alejandro
dc.contributor.authorArrese, Marco
dc.contributor.authorRiquelme, Arnoldo
dc.date.accessioned2024-01-10T14:21:52Z
dc.date.available2024-01-10T14:21:52Z
dc.date.issued2011
dc.description.abstractHepatic epithelioid hemangioendothelioma (HEH) is an unusual, low-grade malignant vascular tumor of the liver. Here we describe a case of a 40-year-old woman who presented with abdominal pain in the upper right quadrant and giant hepatomegaly, in which imaging studies and a fine-needle liver biopsy confirmed the presence of a large EHE with an isolated lung metastasis. After balancing all possible therapeutic modalities the patient was treated conservatively with thalidomide (300 mg/day). The drug was well tolerated with minimal toxicity and the patient continues on therapy 109 months after treatment was started with no disease progression. Current therapeutic options for HEH are discussed in light of the clinical case with particular emphasis on anti-angiogenic therapies.
dc.fechaingreso.objetodigital2025-11-22
dc.format.extent4 páginas
dc.fuente.origenWOS
dc.identifier.issn1665-2681
dc.identifier.pubmedidMEDLINE:21301019
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/79805
dc.identifier.wosidWOS:000289709400018
dc.information.autorucMedicina;Arrese M ;S/I;76095
dc.information.autorucMedicina;Duarte I ;S/I;98528
dc.information.autorucMedicina;Jarufe N ;S/I;104492
dc.information.autorucMedicina;Martinez J ;S/I;65778
dc.information.autorucMedicina;Nervi B ;S/I;604
dc.information.autorucMedicina;Perez R;S/I;100479
dc.information.autorucMedicina;Riquelme A;S/I;3538
dc.information.autorucMedicina;Rodriguez J;S/I;167307
dc.information.autorucMedicina;Soza A;S/I;461
dc.information.autorucMedicina;Valderrama S ;S/I;120766
dc.issue.numero1
dc.language.isoen
dc.nota.accesocontenido completo
dc.pagina.final102
dc.pagina.inicio99
dc.publisherELSEVIER ESPANA
dc.revistaANNALS OF HEPATOLOGY
dc.rightsacceso abierto
dc.subjectHepatic tumors
dc.subjectAnti-angiogenic therapy
dc.subjectEndothelial tumors
dc.subjectLIVER-TRANSPLANTATION
dc.subjectDIAGNOSIS
dc.subjectGROWTH
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleThalidomide for the treatment of metastatic hepatic epithelioid hemangioendothelioma: A case report with a long term follow-up
dc.typeartículo
dc.volumen10
sipa.codpersvinculados76095
sipa.codpersvinculados98528
sipa.codpersvinculados104492
sipa.codpersvinculados65778
sipa.codpersvinculados604
sipa.codpersvinculados100479
sipa.codpersvinculados3538
sipa.codpersvinculados167307
sipa.codpersvinculados461
sipa.codpersvinculados120766
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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