Hypomagnesemia in newborns with hypoxic ischemic encephalopathy and whole-body hypothermia

Simple item page
dc.contributor.authorMaccioni Romero, Andrea
dc.contributor.authorMena Nannig, Patricia
dc.date.accessioned2024-01-10T12:39:30Z
dc.date.available2024-01-10T12:39:30Z
dc.date.issued2020
dc.description.abstractIn newborns with the diagnosis of hypoxic- ischemic encephalopathy (HIE) treated with hypothermia, metabolic alterations are observed, which are associated with neurological prognosis. Hypo-magnesemia has been reported frequently in the literature in these patients, but it is not measured or corrected in all neonatal healthcare centers. Objective: To evaluate the frequency of hypomagnesemia and hypocalcemia in newborns with HIE treated with whole-body hypothermia and to evaluate the response to the magnesium sulfate administration. Patients and Method: Prospective, observational and descriptive study in hospitalized newborns with the diagnosis of HIE and treated with whole-body hypothermia between the years 2016 and 2017. Serial blood measurement of magnesemia (Mg) and calcemia (Ca) was performed. When presenting an Mg level <= 1.8 mg/dl, supplementation with magnesium sulfate was administered to maintain levels between 1.9 and 2.8 mg/dl. The frecuency of hypomagnesemia, hypocalcemia and clinical evolution was registered. A descriptive statistical analysis was performed, with central tendency measures. Results: Sixteen cases were included, 13 of them presented hypomagnesemia (81.3%), with early-onset (6-36 hours of life), which was normalized with magnesium sulfate treatment, receiving a second dose 4 patients. Six of 16 patients presented hypocalcemia (37.5 %). Conclusions: Hypomagnesemia is frequent (80%), similar to that described in the literature, and should be controlled and corrected early, given its physiological role, in the same way that calcium is controlled.
dc.fechaingreso.objetodigital2024-05-09
dc.format.extent6 páginas
dc.fuente.origenWOS
dc.identifier.doi10.32641/rchped.v91i1.1264
dc.identifier.eissn0717-6228
dc.identifier.issn0370-4106
dc.identifier.pubmedidMEDLINE:32730422
dc.identifier.urihttps://doi.org/10.32641/rchped.v91i1.1264
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/77200
dc.identifier.wosidWOS:000529831500016
dc.information.autorucMedicina;Mena Nannig Patricia Isabel;S/I;99768
dc.issue.numero1
dc.language.isoes
dc.nota.accesoSin adjunto
dc.pagina.final121
dc.pagina.inicio116
dc.publisherSOC CHILENA PEDIATRIA
dc.revistaREVISTA CHILENA DE PEDIATRIA-CHILE
dc.rightsregistro bibliográfico
dc.subjectHypoxic-Ischemic
dc.subjectEncephalopathy
dc.subjecthypothermia
dc.subjecthypomagnesemia
dc.subjecthypocalcemia
dc.subjectSERUM MAGNESIUM LEVELS
dc.subjectNEONATAL ENCEPHALOPATHY
dc.subjectPARENTERAL-NUTRITION
dc.subjectANTENATAL MAGNESIUM
dc.subjectCEREBRAL-PALSY
dc.subjectCRITICALLY-ILL
dc.subjectTERM
dc.subjectMULTICENTER
dc.subjectINFANTS
dc.subjectASPHYXIA
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleHypomagnesemia in newborns with hypoxic ischemic encephalopathy and whole-body hypothermia
dc.typeartículo
dc.volumen91
sipa.codpersvinculados99768
sipa.indexWOS
sipa.indexScielo
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Hipomagnesemia en recién nacidos con encefalopatía hipóxico.pdf
Size:
136.68 KB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Artículos de revistas